PMID- 12970461
OWN - NLM
STAT- MEDLINE
DCOM- 20031014
LR  - 20190508
IS  - 0022-538X (Print)
IS  - 1098-5514 (Electronic)
IS  - 0022-538X (Linking)
VI  - 77
IP  - 19
DP  - 2003 Oct
TI  - Detection of a gene cluster that is dispensable for human herpesvirus 6 
      replication and latency.
PG  - 10719-24
AB  - The U3-U7 gene cluster of human herpesvirus 6 (HHV-6) was replaced with an 
      enhanced green fluorescent protein-puromycin gene cassette containing the 
      cytomegalovirus major immediate-early promoter. Neither viral replication in T 
      cells nor latency and reactivation in macrophages was impaired. During HHV-6 
      latency, the cytomegalovirus promoter used the transcription start sites employed 
      in cytomegalovirus latency.
FAU - Kondo, Kazuhiro
AU  - Kondo K
AD  - Department of Microbiology, The Jikei University School of Medicine, Minato-ku, 
      Tokyo, 105-8461, Japan. kkondo@jikei.ac.jp
FAU - Nozaki, Hideo
AU  - Nozaki H
FAU - Shimada, Kazuya
AU  - Shimada K
FAU - Yamanishi, Koichi
AU  - Yamanishi K
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Virol
JT  - Journal of virology
JID - 0113724
SB  - IM
MH  - Cytomegalovirus/genetics
MH  - Genes, Immediate-Early
MH  - HeLa Cells
MH  - Herpesvirus 6, Human/*genetics/physiology
MH  - Humans
MH  - Multigene Family
MH  - Promoter Regions, Genetic
MH  - Virus Activation
MH  - Virus Latency
MH  - Virus Replication
PMC - PMC228414
EDAT- 2003/09/13 05:00
MHDA- 2003/10/15 05:00
PMCR- 2003/10/01
CRDT- 2003/09/13 05:00
PHST- 2003/09/13 05:00 [pubmed]
PHST- 2003/10/15 05:00 [medline]
PHST- 2003/09/13 05:00 [entrez]
PHST- 2003/10/01 00:00 [pmc-release]
AID - 0377 [pii]
AID - 10.1128/jvi.77.19.10719-10724.2003 [doi]
PST - ppublish
SO  - J Virol. 2003 Oct;77(19):10719-24. doi: 10.1128/jvi.77.19.10719-10724.2003.