PMID- 1308828
OWN - NLM
STAT- MEDLINE
DCOM- 19931018
LR  - 20220408
IS  - 0958-7578 (Print)
IS  - 0958-7578 (Linking)
VI  - 2
IP  - 3
DP  - 1992 Sep
TI  - The MAIPA assay and its applications in immunohaematology.
PG  - 181-8
AB  - The monoclonal antibody immobilization of platelet antigens (MAIPA) assay has 
      proved to be a reliable and useful tool in platelet immunology. After 
      immunochemical localization of the most important platelet allo- and autoantigens 
      on platelet glycoproteins (GPs) IIb/IIIa, Ia/IIa, Ib/IX, the corresponding 
      antibodies can easily be detected with this technique because mAbs against these 
      membrane constituents are now readily available. The assay also allows reliable 
      typing of platelet alloantigens. Detection of GP-specific PAIgG (by direct MAIPA) 
      has proved to be a specific diagnostic sign of AITP. The MAIPA assay allowed 
      identification of 'new' alloantibody specificities including alloantibodies 
      against 'low-frequency' antigens. The principle of this technique has 
      successfully been applied to characterize antibodies against lymphocytes, 
      endothelial cells and granulocytes.
FAU - Kiefel, V
AU  - Kiefel V
AD  - Institute for Clinical Immunology and Transfusion Medicine, 
      Justus-Liebig-University, Giessen, Germany.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - England
TA  - Transfus Med
JT  - Transfusion medicine (Oxford, England)
JID - 9301182
RN  - 0 (Antibodies, Monoclonal)
RN  - 0 (Isoantigens)
RN  - 0 (Platelet Membrane Glycoproteins)
SB  - IM
MH  - Antibodies, Monoclonal
MH  - Blood Platelets/*immunology
MH  - Humans
MH  - *Immunoassay/methods
MH  - Isoantigens/*blood
MH  - Platelet Membrane Glycoproteins/immunology
RF  - 55
EDAT- 1992/09/01 00:00
MHDA- 1992/09/01 00:01
CRDT- 1992/09/01 00:00
PHST- 1992/09/01 00:00 [pubmed]
PHST- 1992/09/01 00:01 [medline]
PHST- 1992/09/01 00:00 [entrez]
AID - 10.1111/j.1365-3148.1992.tb00153.x [doi]
PST - ppublish
SO  - Transfus Med. 1992 Sep;2(3):181-8. doi: 10.1111/j.1365-3148.1992.tb00153.x.