PMID- 1308901
OWN - NLM
STAT- MEDLINE
DCOM- 19931021
LR  - 20061115
IS  - 0025-7680 (Print)
IS  - 0025-7680 (Linking)
VI  - 52
IP  - 2
DP  - 1992
TI  - Relationship between enterotoxigenic Escherichia coli and diarrhea among children 
      in Buenos Aires.
PG  - 103-8
AB  - The incidence of enterotoxigenic Escherichia coli (ETEC) has been studied in 85 
      children with acute diarrhea in patients in the Hospital de Ninos Pedro de 
      Elizalde, Buenos Aires, and in 38 healthy children. All of them were up to four 
      years old and none had received antibiotic treatment within 7 days before 
      sampling. ETEC was recovered in 9 out of 85 (10.6%) children with diarrhea. From 
      these positive cases, 6 were associated with heat-stable (ST), 1 with heat-labile 
      (LT) and 2 with both LT and ST enterotoxins. Only one case (2.6%) of LT-producing 
      ETEC was detected in the control group. In 5 out of 9 ETEC diarrhea cases (55.5%) 
      the isolated strains expressed human colonization factor antigens (CFA); four of 
      them were CFA/I and one CFA/II. The characteristics of the CFA, biotype, serotype 
      and antibiotic sensitivity pattern were studied in 23 E. coli isolates from 10 
      ETEC positive children. Of the 12 ST only strains, 5 (41.7%) expressed CFA/I and 
      2 (16.7%) CFA/II (CS2 + CS3). One out of 2 LT/ST strains expressed CFA/I. CFAs 
      were not detected in the ETEC-LT nor in the toxin negative E. coli strains. From 
      the ETEC isolated, 82.4% were resistant to 4 or more antibiotics, whereas only 
      50% of simultaneously isolated toxin-negative E. coli presented this sensitivity 
      pattern. The different ETEC strains belonged to several different serotypes, some 
      of them rarely observed in other countries. None of these serotypes correlated 
      either with the toxin profile or with the sugar fermentation pattern.(ABSTRACT 
      TRUNCATED AT 250 WORDS)
FAU - Binsztein, N
AU  - Binsztein N
AD  - Instituto Nacional de Microbiologia Carlos G. Malbran, Buenos Aires, Argentina.
FAU - Rivas, M
AU  - Rivas M
FAU - Lopez Moral, L
AU  - Lopez Moral L
FAU - Viboud, G
AU  - Viboud G
FAU - Iriarte, C
AU  - Iriarte C
FAU - Szefner, M
AU  - Szefner M
FAU - Svennerholm, A M
AU  - Svennerholm AM
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Argentina
TA  - Medicina (B Aires)
JT  - Medicina
JID - 0204271
RN  - 0 (Bacterial Proteins)
RN  - 0 (Enterotoxins)
RN  - 0 (colonization factor antigens)
RN  - 147680-16-8 (Fimbriae Proteins)
SB  - IM
MH  - Argentina
MH  - Bacterial Proteins/analysis
MH  - Child, Preschool
MH  - Diarrhea, Infantile/*microbiology
MH  - Drug Resistance, Microbial
MH  - Enterotoxins/biosynthesis
MH  - Escherichia coli/drug effects/immunology/isolation & purification
MH  - Escherichia coli Infections/*complications
MH  - *Fimbriae Proteins
MH  - Humans
MH  - Infant
MH  - Infant, Newborn
EDAT- 1992/01/01 00:00
MHDA- 1992/01/01 00:01
CRDT- 1992/01/01 00:00
PHST- 1992/01/01 00:00 [pubmed]
PHST- 1992/01/01 00:01 [medline]
PHST- 1992/01/01 00:00 [entrez]
PST - ppublish
SO  - Medicina (B Aires). 1992;52(2):103-8.