PMID- 1313531
OWN - NLM
STAT- MEDLINE
DCOM- 19920504
LR  - 20041117
IS  - 0391-5352 (Print)
IS  - 0391-5352 (Linking)
VI  - 15
IP  - 1
DP  - 1992 Jan
TI  - IgG antibodies to human herpesvirus-6 (HHV-6) in Italian people.
PG  - 57-63
AB  - Sera from a sample of healthy Italian people were tested in an indirect 
      immunofluorescence assay (IFA) for reactivity to a Human Herpesvirus-6 (HHV-6) 
      strain called CV, isolated from a baby with exanthem subitum (Portolani et al., 
      1990). Seropositivity values of 83.78%, 92.68% and 63.64% were found in subjects 
      aged 3 months-6 years, 6-18 years and over 18 years respectively. Sera from 
      cordal blood, sera from subjects with evidence of active infection by 
      Cytomegalovirus (CMV) or by Epstein-Barr virus (EBV), sera from seropositive 
      adults to Human Immunodeficiency Virus type 1 (HIV) were also investigated for 
      antibodies to the same HHV-6 strain. Values of antibody incidence and antibody 
      content to HHV-6 in these groups of sera were generally higher than in the other 
      groups. HHV-6 reinfections of both endogenous and exogenous origin and antibody 
      cross-reactivity were considered among the reasons of this increase. HHV-6 
      seropositivity values in healthy Italian people and in people from different 
      countries were also discussed in the light of the antigenic characteristics of 
      the HHV-6 strains used and of the different test conditions.
FAU - Cermelli, C
AU  - Cermelli C
AD  - Institute of Hygiene, University of Modena, Italy.
FAU - Moroni, A
AU  - Moroni A
FAU - Pietrosemoli, P
AU  - Pietrosemoli P
FAU - Pecorari, M
AU  - Pecorari M
FAU - Portolani, M
AU  - Portolani M
LA  - eng
PT  - Journal Article
PL  - Italy
TA  - Microbiologica
JT  - Microbiologica
JID - 7902903
RN  - 0 (Antibodies, Viral)
RN  - 0 (Immunoglobulin G)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Age Factors
MH  - Antibodies, Viral/*blood
MH  - Child
MH  - Child, Preschool
MH  - Cross Reactions
MH  - Cytomegalovirus Infections/complications
MH  - Fetal Blood/immunology
MH  - Fluorescent Antibody Technique
MH  - HIV Infections/complications
MH  - Herpesviridae Infections/complications/*epidemiology
MH  - Herpesvirus 6, Human/*immunology
MH  - Humans
MH  - Immunoglobulin G/*blood
MH  - Incidence
MH  - Infant
MH  - Italy/epidemiology
MH  - Prevalence
EDAT- 1992/01/01 00:00
MHDA- 1992/01/01 00:01
CRDT- 1992/01/01 00:00
PHST- 1992/01/01 00:00 [pubmed]
PHST- 1992/01/01 00:01 [medline]
PHST- 1992/01/01 00:00 [entrez]
PST - ppublish
SO  - Microbiologica. 1992 Jan;15(1):57-63.