PMID- 1331116
OWN - NLM
STAT- MEDLINE
DCOM- 19921218
LR  - 20151119
IS  - 0021-9304 (Print)
IS  - 0021-9304 (Linking)
VI  - 26
IP  - 9
DP  - 1992 Sep
TI  - Compositional dependence of calcium phosphate layer formation in fluoride 
      Bioglasses.
PG  - 1147-61
AB  - Bioglasses form a double layer composed of apatite and a silica-rich layer when 
      placed in a simulated physiological solution as well as in living tissue [A.E. 
      Clark, C.G. Pantano, and L. L. Hench, "Auger spectroscopic analysis of bioglass 
      corrosion films," J. Am. Ceram. Soc., 59(1-2), 37-39 (1976).]. In the present 
      work, the mechanisms of the calcium phosphate layer and the silica-rich layer 
      formation of fluoride Bioglasses in Tris-buffer solution are studied as a 
      function of the SiO2 content. Fourier Transform Infrared Reflection Spectroscopy 
      (FTIRS) is used to investigate the mechanism of formation of calcium phosphate 
      and silica-rich layers on the glass surface. Ion concentration in reacted 
      solution and elemental depth profiles are obtained by Induced Coupled Plasma 
      Atomic Emission Spectrometry (ICP) and Auger Electron Spectroscopy (AES), 
      respectively. Si--O bonds with one nonbridging oxygen and Si--O--Si bonds form at 
      the early stage of reaction. Strong phosphorus ion uptake occurs when an 
      amorphous calcium phosphate layer crystallizes. Glasses with high silica content 
      (conventional glass) form the silica-rich layer first followed by a calcium 
      phosphate layer on top. However, glasses with low silica content (invert glass) 
      form both layers simultaneously. The rate of apatite formation decreases with 
      increasing SiO2 content, especially in the region of conventional glass 
      compositions. Ion release rates decreases as SiO2 content increases, with a 
      significant change occurring at the compositional boundary between invert and 
      conventional glasses.
FAU - Kim, C Y
AU  - Kim CY
AD  - Inha University, Inchon, Korea.
FAU - Clark, A E
AU  - Clark AE
FAU - Hench, L L
AU  - Hench LL
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Biomed Mater Res
JT  - Journal of biomedical materials research
JID - 0112726
RN  - 0 (Biocompatible Materials)
RN  - 0 (Bioglass)
RN  - 0 (Calcium Phosphates)
RN  - 0 (Ions)
RN  - 0 (alpha-tricalcium phosphate)
RN  - 0 (amorphous calcium phosphate)
RN  - 0 (tetracalcium phosphate)
RN  - 701EKV9RMN (calcium phosphate, monobasic, anhydrous)
RN  - 7631-86-9 (Silicon Dioxide)
RN  - 97Z1WI3NDX (calcium phosphate)
RN  - L11K75P92J (calcium phosphate, dibasic, anhydrous)
RN  - Q80VPU408O (Fluorides)
SB  - IM
MH  - Biocompatible Materials/*chemistry
MH  - Calcium Phosphates/*chemistry
MH  - Ceramics/*chemistry
MH  - Fluorides/*chemistry
MH  - Fourier Analysis
MH  - Ions
MH  - Silicon Dioxide/analysis
MH  - Spectrophotometry, Infrared
EDAT- 1992/09/01 00:00
MHDA- 1992/09/01 00:01
CRDT- 1992/09/01 00:00
PHST- 1992/09/01 00:00 [pubmed]
PHST- 1992/09/01 00:01 [medline]
PHST- 1992/09/01 00:00 [entrez]
AID - 10.1002/jbm.820260905 [doi]
PST - ppublish
SO  - J Biomed Mater Res. 1992 Sep;26(9):1147-61. doi: 10.1002/jbm.820260905.