PMID- 1341875
OWN - NLM
STAT- MEDLINE
DCOM- 19940125
LR  - 20131121
IS  - 0066-782X (Print)
IS  - 0066-782X (Linking)
VI  - 59
IP  - 6
DP  - 1992 Dec
TI  - [Captopril in the treatment of patients with congestive heart failure. Its 
      bicycle ergometry evaluation].
PG  - 487-91
AB  - PURPOSE: To analyze the physical performance of the patients with congestive 
      heart failure (CHF), grades I and II of the New York Heart Association (NYHA), 
      submitted to ergometric test: 1) under conventional treatment with digitalis and 
      diuretic; 2) with an angiotensin converting enzyme inhibitor, captopril, 
      associate with conventional treatment; 3) using captopril associated with 
      digitalis or diuretic. METHODS: A randomized double blind study was performed in 
      20 patients with CHF (I and II-NYHA) submitted to ergometric test in different 
      therapeutic phases. The initial workload was 5 watts and load was increased until 
      the appearance of limiting symptoms. RESULTS: The introduction of captopril to 
      the conventional treatment for CHF or associated with digitalis or diuretic 
      promotes significant increase in the duration of the physical exercise, in the 
      oxygen consumption and in the total workload during the ergometric test. 
      CONCLUSION: In the initial forms of CHF, captopril provides better physical 
      performance when compared with conventional treatment and the diuretic treatment 
      can be changed for the angiotensin converting enzyme inhibitor with equal 
      efficacy.
FAU - Ferreira Filho, S R
AU  - Ferreira Filho SR
AD  - Universidade Federal de Uberlandia, MG, Universidade Federal do Espirito Santo.
FAU - Hatab, S A
AU  - Hatab SA
FAU - Benchimol, C
AU  - Benchimol C
FAU - Nascimento, L O
AU  - Nascimento LO
FAU - Saragoca, M A
AU  - Saragoca MA
LA  - por
PT  - Clinical Trial
PT  - Comparative Study
PT  - English Abstract
PT  - Journal Article
PT  - Randomized Controlled Trial
TT  - Captopril no tratamento de pacientes com insuficiencia cardiaca congestiva. 
      Avaliacao cicloergometrica.
PL  - Brazil
TA  - Arq Bras Cardiol
JT  - Arquivos brasileiros de cardiologia
JID - 0421031
RN  - 7LXU5N7ZO5 (Furosemide)
RN  - 9G64RSX1XD (Captopril)
RN  - E90NZP2L9U (Digitoxin)
SB  - IM
MH  - Analysis of Variance
MH  - Captopril/*therapeutic use
MH  - Chronic Disease
MH  - Digitoxin/therapeutic use
MH  - Double-Blind Method
MH  - Drug Therapy, Combination
MH  - Exercise Test/statistics & numerical data
MH  - Female
MH  - Furosemide/therapeutic use
MH  - Heart Failure/*drug therapy/epidemiology/physiopathology
MH  - Humans
MH  - Male
MH  - Middle Aged
EDAT- 1992/12/01 00:00
MHDA- 1992/12/01 00:01
CRDT- 1992/12/01 00:00
PHST- 1992/12/01 00:00 [pubmed]
PHST- 1992/12/01 00:01 [medline]
PHST- 1992/12/01 00:00 [entrez]
PST - ppublish
SO  - Arq Bras Cardiol. 1992 Dec;59(6):487-91.