PMID- 1342879
OWN - NLM
STAT- MEDLINE
DCOM- 19940222
LR  - 20130731
IS  - 1018-9068 (Print)
IS  - 1018-9068 (Linking)
VI  - 2
IP  - 1
DP  - 1992 Jan-Feb
TI  - Subacute cutaneous lupus erythematosus--clinical, histopathological and 
      immunophenotypical study of five cases.
PG  - 27-32
AB  - Subacute cutaneous lupus erythematosus (SCLE) is a recently described distinct 
      subset of lupus erythematosus (LE) having characteristic clinical, serological 
      and genetic features. The clinicopathological and serological findings of 5 
      patients are reported. From a clinical point of view, we describe two types of 
      cutaneous lesions: psoriasiform and annular pattern. ANA were present in 80% of 
      the cases, anti-Ro was present in 60%, and anti-La in 20%; anti-RNP was positive 
      in 1 patient. Circulating immune complexes were detected in 2 patients, and low 
      levels of complement factors (C3, C4) in another 2 patients. The B- cell 
      alloantigens HLA-A2, HLA-Bw4 or HLA-DR3 were present in 60% of the cases. The 
      cutaneous histopathology revealed important changes in the epidermis. Our 
      findings are similar to those described by most other authors. Also, we would 
      like to emphasize the low disease activity and benign course of our patients.
FAU - Vazquez-Doval, J
AU  - Vazquez-Doval J
AD  - Department of Dermatology, University of Navarra, Pamplona, Spain.
FAU - Ruiz de Erenchun, F
AU  - Ruiz de Erenchun F
FAU - Sanchez-Ibarrola, A
AU  - Sanchez-Ibarrola A
FAU - Contreras, F
AU  - Contreras F
FAU - Soto de Delas, J
AU  - Soto de Delas J
FAU - Quintanilla, E
AU  - Quintanilla E
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Spain
TA  - J Investig Allergol Clin Immunol
JT  - Journal of investigational allergology & clinical immunology
JID - 9107858
RN  - 0 (Antibodies, Antinuclear)
RN  - 0 (HLA Antigens)
SB  - IM
MH  - Adult
MH  - Antibodies, Antinuclear/blood
MH  - Female
MH  - HLA Antigens
MH  - Humans
MH  - Lupus Erythematosus, Cutaneous/*immunology/*pathology
MH  - Male
MH  - Middle Aged
MH  - Phenotype
MH  - Skin/pathology
EDAT- 1992/01/01 00:00
MHDA- 1992/01/01 00:01
CRDT- 1992/01/01 00:00
PHST- 1992/01/01 00:00 [pubmed]
PHST- 1992/01/01 00:01 [medline]
PHST- 1992/01/01 00:00 [entrez]
PST - ppublish
SO  - J Investig Allergol Clin Immunol. 1992 Jan-Feb;2(1):27-32.