PMID- 1347432
OWN - NLM
STAT- MEDLINE
DCOM- 19920409
LR  - 20221207
IS  - 0001-2815 (Print)
IS  - 0001-2815 (Linking)
VI  - 39
IP  - 1
DP  - 1992 Jan
TI  - Analysis of HLA class II allogenotyping in Australian aborigines and Papua New 
      Guinea populations.
PG  - 1-7
AB  - Human leukocyte antigen (HLA) class II allogenotyping has been applied to 
      investigate the polymorphism of the DRB, DQB1, DQB2, DQA1, and DQA2 genes in 
      Aborigines from the East Coast of Australia and in Melanesians from the Papua New 
      Guinea North-East Coast and Highlands. Three new DR/DQ arrangements were 
      observed, DRw14/DQB1-2b/DQA1-1a and DRw5Nauru/DQB1-3a/DQA1-2 (n Australian 
      Aborigines), and DRw5Nauru/DQB1-1a/DQA1-1b (in Madang). DQA2 and DQB2 
      allogenotyping with TaqI and PstI digested genomic DNA revealed little 
      polymorphism among the Papua New Guineans, with DQA2-Xa1 and DQB2-Xb1 the most 
      common alleles in all the groups. However, the presence of DQA2-Xa2 in Papuans 
      and Australian Aborigines reflects the degree of admixture with Caucasoids while 
      the DQA2-Xa4 allele in Madang is probably a marker of Mongoloid origin.
FAU - Trejaut, J
AU  - Trejaut J
AD  - Tissue Typing, Red Cross, Blood Transfusion Service, Sydney, Australia.
FAU - Dunckley, H
AU  - Dunckley H
FAU - Sullivan, J
AU  - Sullivan J
FAU - Kennedy, C
AU  - Kennedy C
FAU - Crane, G
AU  - Crane G
LA  - eng
PT  - Journal Article
PL  - England
TA  - Tissue Antigens
JT  - Tissue antigens
JID - 0331072
RN  - 0 (DNA Probes, HLA)
RN  - 0 (HLA-DQ Antigens)
RN  - 0 (HLA-DR Antigens)
SB  - IM
GS  - BQB2
GS  - DQA1
GS  - DQA2
GS  - DQB1
GS  - DRB
MH  - Asian People/genetics
MH  - Australia
MH  - Black People/genetics
MH  - DNA Probes, HLA/genetics
MH  - Gene Frequency
MH  - *Genes, MHC Class II
MH  - Genetic Linkage
MH  - HLA-DQ Antigens/*genetics
MH  - HLA-DR Antigens/*genetics
MH  - Humans
MH  - *Native Hawaiian or Other Pacific Islander/*genetics
MH  - Papua New Guinea
MH  - Polymorphism, Restriction Fragment Length
MH  - Racial Groups/*genetics
MH  - White People/*genetics
EDAT- 1992/01/01 00:00
MHDA- 1992/01/01 00:01
CRDT- 1992/01/01 00:00
PHST- 1992/01/01 00:00 [pubmed]
PHST- 1992/01/01 00:01 [medline]
PHST- 1992/01/01 00:00 [entrez]
AID - 10.1111/j.1399-0039.1992.tb02147.x [doi]
PST - ppublish
SO  - Tissue Antigens. 1992 Jan;39(1):1-7. doi: 10.1111/j.1399-0039.1992.tb02147.x.