PMID- 1350613 OWN - NLM STAT- MEDLINE DCOM- 19920702 LR - 20190724 IS - 0022-3018 (Print) IS - 0022-3018 (Linking) VI - 180 IP - 6 DP - 1992 Jun TI - Phenomenology and sequelae of 3,4-methylenedioxymethamphetamine use. PG - 345-52; discussion 353-4 AB - 3,4-Methylenedioxymethamphetamine (MDMA) has been at the center of a debate over its potential benefits as an adjunct to psychotherapy versus its capability for neurotoxic effects and is currently classified as a Schedule 1 drug by the Drug Enforcement Administration (DEA). However, as yet, there is very little methodological data on the subjective experience of the MDMA-induced state or its psychological and behavioral sequelae. The present study was, therefore, designed to obtain this kind of information. Twenty psychiatrists who had taken MDMA previously were evaluated using a semistructured interview. Subjective experience of the actual MDMA-induced state, as well as both short-term (less than 1 week) and relatively longer term (greater than 1 week) sequelae, were examined retrospectively. Side effects, insight gained, pleasure, and intensity of the MDMA experience were evaluated as were the influence of set and setting at the time the MDMA was taken and the dosage utilized. Finally, the authors discuss methodological problems and limitations of a study of this type. FAU - Liester, M B AU - Liester MB AD - Department of Psychiatry, University of California, Irvine Medical Center, Orange 92668. FAU - Grob, C S AU - Grob CS FAU - Bravo, G L AU - Bravo GL FAU - Walsh, R N AU - Walsh RN LA - eng PT - Journal Article PL - United States TA - J Nerv Ment Dis JT - The Journal of nervous and mental disease JID - 0375402 RN - 0 (Designer Drugs) RN - 4764-17-4 (3,4-Methylenedioxyamphetamine) RN - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine) SB - IM MH - 3,4-Methylenedioxyamphetamine/adverse effects/*analogs & derivatives/pharmacology/therapeutic use MH - Adult MH - Combined Modality Therapy MH - Designer Drugs/adverse effects/*pharmacology/therapeutic use MH - Emotions/drug effects MH - Female MH - Humans MH - Interpersonal Relations MH - Male MH - Mental Disorders/chemically induced/drug therapy MH - Middle Aged MH - N-Methyl-3,4-methylenedioxyamphetamine MH - Nervous System/drug effects MH - Perception/drug effects MH - Psychotherapy MH - Research Design/standards MH - Substance-Related Disorders/*psychology EDAT- 1992/06/01 00:00 MHDA- 1992/06/01 00:01 CRDT- 1992/06/01 00:00 PHST- 1992/06/01 00:00 [pubmed] PHST- 1992/06/01 00:01 [medline] PHST- 1992/06/01 00:00 [entrez] AID - 10.1097/00005053-199206000-00001 [doi] PST - ppublish SO - J Nerv Ment Dis. 1992 Jun;180(6):345-52; discussion 353-4. doi: 10.1097/00005053-199206000-00001.