PMID- 13739553
OWN - NLM
STAT- MEDLINE
DCOM- 19981101
LR  - 20181130
IS  - 0008-1264 (Print)
IS  - 0008-1264 (Linking)
VI  - 93
IP  - 4
DP  - 1960 Oct
TI  - The antihemophilic globulin in plasma; content of freshly frozen single-donor 
      plasma units prepared by the Los Angeles Red Cross Blood Center.
PG  - 208-10
AB  - A study was made of the antihemophilic globulin (AHG) content of 16 units of 
      freshly frozen, single-donor, type specific plasma prepared by the Los Angeles 
      Red Cross Blood Center for the treatment of patients with coagulation disorders. 
      Three specimens were examined for each unit-(1) a control sample taken from the 
      donor in a separate small tube, (2) a plasma unit sample before storage, and (3) 
      a plasma unit sample after storage for periods up to one year. From a comparison 
      of the AHG content of Samples 1 and 2, it was found that little AHG was lost in 
      preparing the plasma units. From a comparison of Samples 2 and 3, it was found 
      that a moderate AHG loss (averaging about 20 per cent) occurs on storage. This 
      varied unpredictably from bottle to bottle and was unrelated to the duration of 
      storage. Good AHG activity was found in 4 units after storage for one year. An 
      individual unit of frozen plasma from the Los Angeles Red Cross Blood Center will 
      contain between 50 and 115 per cent AHG activity (with a standard reference 
      sample of plasma taken as 100 per cent).
FAU - RAPAPORT, S I
AU  - RAPAPORT SI
FAU - PATCH, M J
AU  - PATCH MJ
FAU - CASEY, J E
AU  - CASEY JE
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Calif Med
JT  - California medicine
JID - 0410260
RN  - 0 (Serum Globulins)
RN  - 9001-27-8 (Factor VIII)
SB  - OM
MH  - *Blood Coagulation Tests
MH  - *Blood Preservation
MH  - *Factor VIII
MH  - *Freezing
MH  - Hemophilia A/*therapy
MH  - Humans
MH  - Los Angeles
MH  - *Plasma
MH  - *Red Cross
MH  - *Serum Globulins
MH  - *Tissue Donors
PMC - PMC1578423
OTO - NLM
OT  - *BLOOD PRESERVATION
OT  - *HEMOPHILIA/therapy
OT  - *SERUM GLOBULIN
EDAT- 1960/10/01 00:00
MHDA- 1960/10/01 00:01
PMCR- 1960/10/01
CRDT- 1960/10/01 00:00
PHST- 1960/10/01 00:00 [pubmed]
PHST- 1960/10/01 00:01 [medline]
PHST- 1960/10/01 00:00 [entrez]
PHST- 1960/10/01 00:00 [pmc-release]
PST - ppublish
SO  - Calif Med. 1960 Oct;93(4):208-10.