PMID- 1389815
OWN - NLM
STAT- MEDLINE
DCOM- 19921029
LR  - 20190515
IS  - 0007-0912 (Print)
IS  - 0007-0912 (Linking)
VI  - 69
IP  - 2
DP  - 1992 Aug
TI  - Risk factors for oxygen desaturation during sleep, after abdominal surgery.
PG  - 137-42
AB  - The postoperative period after major abdominal surgery is known to be a period of 
      increased episodic oxygen desaturation. In order to assess the risk factors for 
      episodic desaturation, we have studied 29 surgical patients using pulse oximetry 
      during the preoperative night (Npre) when they received benzodiazepine 
      premedication and breathed air, and also during the first three nights after 
      operation when they received nasal oxygen supplementation. Modal oxygen 
      saturation (SpO2) exceeded 95% during all nights studied. The time spent at less 
      than 90% (t90) and 85% (t85) SpO2 and the average SpO2 nadir (SpO2, nadir) did 
      not differ each night. Heart rate was greater (mean 90.1 (SD 16.6) vs 68.2 (12.0) 
      beat min-1, P < 0.001) during the second night after operation (N2) than during 
      Npre. Before operation, the number of desaturations, t90 and t85 correlated with 
      pharyngeal hypertrophy (P = 0.003, P = 0.002, P = 0.001, respectively). At the 
      same time, t90 and t85 correlated with body mass index (P = 0.02 and P = 0.05, 
      respectively). During N2, t90 correlated with radiological lung consolidation (P 
      = 0.05) and SpO2, nadir correlated with FEV1 (P = 0.03). We conclude that there 
      are several mechanisms responsible for oxygen desaturation and that these 
      mechanisms differ before and after surgery.
FAU - Beydon, L
AU  - Beydon L
AD  - Service d'Anesthesie-Reanimation, Hopital Henri Mondor, Creteil, France.
FAU - Hassapopoulos, J
AU  - Hassapopoulos J
FAU - Quera, M A
AU  - Quera MA
FAU - Rauss, A
AU  - Rauss A
FAU - Becquemin, J P
AU  - Becquemin JP
FAU - Bonnet, F
AU  - Bonnet F
FAU - Harf, A
AU  - Harf A
FAU - Goldenberg, F
AU  - Goldenberg F
LA  - eng
PT  - Journal Article
PL  - England
TA  - Br J Anaesth
JT  - British journal of anaesthesia
JID - 0372541
RN  - S88TT14065 (Oxygen)
SB  - IM
MH  - Abdomen/*surgery
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Female
MH  - Heart Rate
MH  - Humans
MH  - Hypoxia/blood/*etiology
MH  - Male
MH  - Middle Aged
MH  - Oximetry
MH  - Oxygen/*blood/therapeutic use
MH  - *Postoperative Complications/blood
MH  - Risk Factors
MH  - *Sleep
MH  - Snoring/physiopathology
EDAT- 1992/08/01 00:00
MHDA- 1992/08/01 00:01
CRDT- 1992/08/01 00:00
PHST- 1992/08/01 00:00 [pubmed]
PHST- 1992/08/01 00:01 [medline]
PHST- 1992/08/01 00:00 [entrez]
AID - S0007-0912(17)46490-7 [pii]
AID - 10.1093/bja/69.2.137 [doi]
PST - ppublish
SO  - Br J Anaesth. 1992 Aug;69(2):137-42. doi: 10.1093/bja/69.2.137.