PMID- 1399012
OWN - NLM
STAT- MEDLINE
DCOM- 19921106
LR  - 20190907
IS  - 0340-0131 (Print)
IS  - 0340-0131 (Linking)
VI  - 64
IP  - 1
DP  - 1992
TI  - Immunological findings and respiratory function in cotton textile workers.
PG  - 31-7
AB  - Immunological parameters were studied in a group of 24 cotton textile workers. 
      These were volunteers from a cohort of 106 (83 women and 23 men) previously 
      studied textile workers. A group of 30 employees from a bottle packing plant 
      served as a control for the immunologic studies. The subgroup of volunteers 
      undergoing immunologic testing did not differ from the original cohort of textile 
      workers in age, sex, smoking history, or prevalence of most chronic respiratory 
      symptoms, nor were there any significant differences in baseline lung function or 
      across-shift changes. The 24 cotton worker volunteers underwent skin testing with 
      extracts of cotton dust and cotton seed. Eight of these 24 (33.3%) had positive 
      tests, and 5 of the 8 had elevated serum immunoglobulin E (IgE) levels. Only one 
      of the 8 skin-test-positive workers had symptoms of byssinosis. Only 1 of 30 
      control workers' skin tested with cotton extract reacted, and none had an 
      increased serum IgE level (P less than 0.01). Both baseline lung function and 
      across-shift changes did not differ between workers with positive and negative 
      skin test reactions or between workers with normal and elevated IgE levels. 
      Additionally, we studied the response in vitro of nonsensitized guinea pig 
      trachea to cotton bract extract and demonstrated a dose-dependent contractile 
      response. These data suggest that while immunological findings are frequent in 
      textile workers, they correlate poorly with respiratory symptoms and function and 
      may not be the basis for the airway obstruction seen in this disease.
FAU - Zuskin, E
AU  - Zuskin E
AD  - Andrija Stampar School of Public Health, Zagreb, Yugoslavia.
FAU - Kanceljak, B
AU  - Kanceljak B
FAU - Schachter, E N
AU  - Schachter EN
FAU - Witek, T J
AU  - Witek TJ
FAU - Mustajbegovic, J
AU  - Mustajbegovic J
FAU - Maayani, S
AU  - Maayani S
FAU - Buck, M G
AU  - Buck MG
FAU - Rienzi, N
AU  - Rienzi N
LA  - eng
GR  - R01 OHO 2593-O1A1/OH/NIOSH CDC HHS/United States
GR  - YF 733/PHS HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - Germany
TA  - Int Arch Occup Environ Health
JT  - International archives of occupational and environmental health
JID - 7512134
RN  - 0 (Air Pollutants, Occupational)
RN  - 0 (Dust)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adult
MH  - Air Pollutants, Occupational/analysis
MH  - Chronic Disease
MH  - Cohort Studies
MH  - Dust/*adverse effects/analysis
MH  - Female
MH  - Gossypium/adverse effects/*immunology
MH  - Humans
MH  - Immunoglobulin E/*blood
MH  - Male
MH  - Occupational Diseases/epidemiology/etiology/*immunology
MH  - Prevalence
MH  - Pulmonary Ventilation/immunology
MH  - Respiratory Tract Diseases/epidemiology/etiology/*immunology
MH  - *Textile Industry
MH  - Vital Capacity/immunology
EDAT- 1992/01/01 00:00
MHDA- 1992/01/01 00:01
CRDT- 1992/01/01 00:00
PHST- 1992/01/01 00:00 [pubmed]
PHST- 1992/01/01 00:01 [medline]
PHST- 1992/01/01 00:00 [entrez]
AID - 10.1007/BF00625948 [doi]
PST - ppublish
SO  - Int Arch Occup Environ Health. 1992;64(1):31-7. doi: 10.1007/BF00625948.