PMID- 1400008
OWN - NLM
STAT- MEDLINE
DCOM- 19921112
LR  - 20220409
IS  - 8750-7587 (Print)
IS  - 0161-7567 (Linking)
VI  - 73
IP  - 2
DP  - 1992 Aug
TI  - Protein requirements and muscle mass/strength changes during intensive training 
      in novice bodybuilders.
PG  - 767-75
AB  - This randomized double-blind cross-over study assessed protein (PRO) requirements 
      during the early stages of intensive bodybuilding training and determined whether 
      supplemental PRO intake (PROIN) enhanced muscle mass/strength gains. Twelve men 
      [22.4 +/- 2.4 (SD) yr] received an isoenergetic PRO (total PROIN 2.62 
      g.kg-1.day-1) or carbohydrate (CHO; total PROIN 1.35 g.kg-1.day-1) supplement for 
      1 mo each during intensive (1.5 h/day, 6 days/wk) weight training. On the basis 
      of 3-day nitrogen balance (NBAL) measurements after 3.5 wk on each treatment (8.9 
      +/- 4.2 and -3.4 +/- 1.9 g N/day, respectively), the PROIN necessary for zero 
      NBAL (requirement) was 1.4-1.5 g.kg-1.day-1. The recommended intake (requirement 
      + 2 SD) was 1.6-1.7 g.kg-1.day-1. However, strength (voluntary and electrically 
      evoked) and muscle mass [density, creatinine excretion, muscle area (computer 
      axial tomography scan), and biceps N content] gains were not different between 
      diet treatments. These data indicate that, during the early stages of intensive 
      bodybuilding training, PRO needs are approximately 100% greater than current 
      recommendations but that PROIN increases from 1.35 to 2.62 g.kg-1.day-1 do not 
      enhance muscle mass/strength gains, at least during the 1st mo of training. 
      Whether differential gains would occur with longer training remains to be 
      determined.
FAU - Lemon, P W
AU  - Lemon PW
AD  - School of Biomedical Sciences, Kent State University, Ohio 44242.
FAU - Tarnopolsky, M A
AU  - Tarnopolsky MA
FAU - MacDougall, J D
AU  - MacDougall JD
FAU - Atkinson, S A
AU  - Atkinson SA
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Appl Physiol (1985)
JT  - Journal of applied physiology (Bethesda, Md. : 1985)
JID - 8502536
RN  - 0 (Dietary Proteins)
RN  - N762921K75 (Nitrogen)
SB  - IM
MH  - Adult
MH  - Body Weight/physiology
MH  - Diet
MH  - Dietary Proteins/*pharmacology
MH  - Double-Blind Method
MH  - Energy Metabolism
MH  - Humans
MH  - Male
MH  - Muscles/anatomy & histology/innervation/*physiology
MH  - Nitrogen/metabolism
MH  - *Nutritional Requirements
MH  - Organ Size/physiology
MH  - Tomography, X-Ray Computed
MH  - *Weight Lifting
EDAT- 1992/08/01 00:00
MHDA- 1992/08/01 00:01
CRDT- 1992/08/01 00:00
PHST- 1992/08/01 00:00 [pubmed]
PHST- 1992/08/01 00:01 [medline]
PHST- 1992/08/01 00:00 [entrez]
AID - 10.1152/jappl.1992.73.2.767 [doi]
PST - ppublish
SO  - J Appl Physiol (1985). 1992 Aug;73(2):767-75. doi: 10.1152/jappl.1992.73.2.767.