PMID- 1400016 OWN - NLM STAT- MEDLINE DCOM- 19921123 LR - 20171213 IS - 8750-7587 (Print) IS - 0161-7567 (Linking) VI - 73 IP - 3 DP - 1992 Sep TI - Respiration and measurement of cardiac output by thermodilution and central or peripheral dye dilution. PG - 1047-51 AB - Cardiac output as measured by indicator dilution methods during artificial ventilation shows differences up to +/- 35%. We studied the influence of spontaneous breathing on measurement of cardiac output by thermodilution (TD) and central (CDD) and peripheral dye dilution (PDD) in seven anesthetized dogs. Injection of indicator was timed at one of five chosen moments in a respiratory cycle. The indicator for TD was also used as solvent for indocyanine green. Results were normalized by the value obtained with injection at inspiratory onset. Results of the central dilution methods showed a slight but not significant difference between values measured with injection at 25 and 75% of the respiratory cycle: 105.7 and 98.0%, respectively, (TD) and 102.3 and 97.2% (CDD). Mean cardiac output determined by TD, CDD, or PDD was not significantly different. We conclude that 1) a reasonable estimate of cardiac output may be obtained by means of a single indicator-dilution curve and 2) the choice of the dilution method may be determined by practical considerations. FAU - Delhaas, T AU - Delhaas T AD - Department of Medical Physiology, University of Groningen, The Netherlands. FAU - Mook, G A AU - Mook GA FAU - Zijlstra, W G AU - Zijlstra WG LA - eng PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - J Appl Physiol (1985) JT - Journal of applied physiology (Bethesda, Md. : 1985) JID - 8502536 SB - IM MH - Animals MH - Cardiac Output/*physiology MH - Dogs MH - Dye Dilution Technique MH - Evaluation Studies as Topic MH - Female MH - *Indicator Dilution Techniques MH - Male MH - Respiration/*physiology MH - Thermodilution EDAT- 1992/09/01 00:00 MHDA- 1992/09/01 00:01 CRDT- 1992/09/01 00:00 PHST- 1992/09/01 00:00 [pubmed] PHST- 1992/09/01 00:01 [medline] PHST- 1992/09/01 00:00 [entrez] AID - 10.1152/jappl.1992.73.3.1047 [doi] PST - ppublish SO - J Appl Physiol (1985). 1992 Sep;73(3):1047-51. doi: 10.1152/jappl.1992.73.3.1047.