PMID- 1415859
OWN - NLM
STAT- MEDLINE
DCOM- 19921026
LR  - 20221207
IS  - 0090-0036 (Print)
IS  - 1541-0048 (Electronic)
IS  - 0090-0036 (Linking)
VI  - 82
IP  - 10
DP  - 1992 Oct
TI  - Lead exposure and child behavior.
PG  - 1356-60
AB  - OBJECTIVES: Unlike cognitive impairments associated with lead exposure, 
      lead-associated child behavior problems have been difficult to specify, 
      particularly in young children. METHODS: The Child Behavior Checklist (CBCL) and 
      the Center for Epidemiologic Studies Depression Scale were used as the outcome 
      and confounding variables, respectively, of major interest. These measures were 
      examined with respect to blood lead levels of 201 African-American children aged 
      2 through 5 years. RESULTS: In comparison with the low exposed group, the high 
      exposed group (two consecutive blood lead levels greater than or equal to 15 
      micrograms/dL) had a significantly higher mean CBCL Total Behavior Problem Score 
      (TBPS) and Internalizing and Externalizing scores; when other factors, including 
      maternal depressive symptomatology, were controlled for, regression procedures 
      indicated a .18-point TBPS increase for each unit increase in lead and a 
      5.1-point higher TBPS in the high exposed group; children in this group were 2.7 
      times more likely to have a TBPS in the clinical range. CONCLUSIONS: Through its 
      use of a standardized parent-report measure of behavior and its consideration of 
      maternal morale in multiple linear and logistic regression procedures, this study 
      provides further evidence of lead's detrimental effect on child behavior at 
      levels typical of present-day exposure.
FAU - Sciarillo, W G
AU  - Sciarillo WG
AD  - Children's Medical Services, Department of Health and Mental Hygiene, Baltimore, 
      Md.
FAU - Alexander, G
AU  - Alexander G
FAU - Farrell, K P
AU  - Farrell KP
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Am J Public Health
JT  - American journal of public health
JID - 1254074
RN  - 2P299V784P (Lead)
SB  - IM
MH  - Academies and Institutes
MH  - Black or African American
MH  - Baltimore/epidemiology
MH  - Child
MH  - Child Behavior Disorders/diagnosis/*epidemiology/etiology
MH  - Child, Preschool
MH  - Depressive Disorder/epidemiology
MH  - Educational Status
MH  - Evaluation Studies as Topic
MH  - Family Characteristics
MH  - Female
MH  - Humans
MH  - Interviews as Topic
MH  - Lead/blood
MH  - Lead Poisoning/blood/*complications
MH  - Linear Models
MH  - Logistic Models
MH  - Male
MH  - Marital Status
MH  - Mothers/education/psychology/statistics & numerical data
MH  - Occupations
MH  - Prevalence
MH  - Referral and Consultation
MH  - Risk Factors
MH  - Seroepidemiologic Studies
PMC - PMC1695858
EDAT- 1992/10/01 00:00
MHDA- 1992/10/01 00:01
PMCR- 1994/10/01
CRDT- 1992/10/01 00:00
PHST- 1992/10/01 00:00 [pubmed]
PHST- 1992/10/01 00:01 [medline]
PHST- 1992/10/01 00:00 [entrez]
PHST- 1994/10/01 00:00 [pmc-release]
AID - 10.2105/ajph.82.10.1356 [doi]
PST - ppublish
SO  - Am J Public Health. 1992 Oct;82(10):1356-60. doi: 10.2105/ajph.82.10.1356.