PMID- 1417351 OWN - NLM STAT- MEDLINE DCOM- 19921117 LR - 20061115 IS - 0020-3785 (Print) VI - 62 IP - 4 DP - 1992 Jul-Aug TI - [Late results of mitral valve replacement in 155 subjects under 16 years of age. Comparative study with 4 prosthesis]. PG - 333-8 AB - We followed 155 children aged 6 to 16 years who underwent mitral valve replacement for rheumatic heart disease. Group I included 74 patients with Starr-Edwards prostheses and the mean follow-up period was 13 years. Group II was formed by 36 patients with Bjork-Shiley prostheses and a mean follow-up of 7.5 years. Group III consisted of 31 children with dura mater bioprostheses and a mean follow-up of 5.1 years. Finally, group IV included 14 patients followed a mean period of 4.9 years with Hancock xenografts. The four groups of patients were comparable before surgery. The criteria of the New York Heart Association (NYHA) were used to evaluate all patients before and 12 months after surgery. All patients with mechanical prostheses received anticoagulant therapy with acenocumarol from the first postoperative day. The incidence of complications such as thromboembolism, infective endocarditis, prosthetic dysfunction and death were determined at the end of the follow-up. The Fisher's exact test was used for nonparametric analysis and the two-tailed Student's T test for parametric results. All but two patients improved their NYHA clinical status after surgery (p less than 0.0001). Forty eight patients with mechanical prostheses were catheterized 1 to 7 years after the operation. The mean pulmonary arterial systolic pressure was reduced from 58 mmHg to 30 mmHg (p less than 0.001) and the mean pulmonary arterial wedge pressure decreased from 22 mmHg to 11 mmHg (p less than 0.001). There were no significant differences between the groups with mechanical and tissue prostheses in the incidence of thromboembolism and infective endocarditis.(ABSTRACT TRUNCATED AT 250 WORDS) FAU - Zabal, C AU - Zabal C AD - Instituto Nacional de Cardiologia Ignacio Chavez, Mexico, D.F. FAU - Attie, F AU - Attie F FAU - Barragan, R AU - Barragan R FAU - Buendia, A AU - Buendia A FAU - Pena Duque, M AU - Pena Duque M LA - spa PT - Comparative Study PT - English Abstract PT - Journal Article TT - Resultado tardio del cambio valvular mitral en 155 sujetos menores de 16 anos. Estudio comparativo con cuatro protesis. PL - Mexico TA - Arch Inst Cardiol Mex JT - Archivos del Instituto de Cardiologia de Mexico JID - 0400463 SB - IM MH - Adolescent MH - *Bioprosthesis MH - Child MH - *Heart Valve Prosthesis MH - Humans MH - Mitral Valve MH - Postoperative Care MH - *Postoperative Complications/mortality MH - Preoperative Care MH - Prosthesis Failure MH - Reoperation MH - Time Factors EDAT- 1992/07/01 00:00 MHDA- 1992/07/01 00:01 CRDT- 1992/07/01 00:00 PHST- 1992/07/01 00:00 [pubmed] PHST- 1992/07/01 00:01 [medline] PHST- 1992/07/01 00:00 [entrez] PST - ppublish SO - Arch Inst Cardiol Mex. 1992 Jul-Aug;62(4):333-8.