PMID- 142574
OWN - NLM
STAT- MEDLINE
DCOM- 19771020
LR  - 20181130
IS  - 0037-9026 (Print)
IS  - 0037-9026 (Linking)
VI  - 171
IP  - 2
DP  - 1977
TI  - [Simultaneous liberation of vasopressin (ADH) and of neurophysins during nicotine 
      perfusion in man].
PG  - 478-83
AB  - Using the radioimmunoassay (R.I.A.) for neurophysins (I.R.N.) described in 1969, 
      we demonstrated a concomitant, rapid release of both A.D.H. and I.R.N. within the 
      first minutes (2') of the i.v. infusion of nicotine in 11 patients with normal 
      neuropituitary function and 1 patient suffering from a Schwartz-Bartter syndrome. 
      There is a close relationship (r : 0,82, p less than 0.001) similar to that 
      described by other authors, between peak levels of A.D.H. and I.R.N. in all the 
      patients. Hence, we proved that our R.I.A. system is influenced by nicotine 
      stimulated neurophysins (N.S.N.). The negative results previously published by 
      two of us in 5 normal men could have been due to the length of the period between 
      the beginning of the test and the first blood sampling (30 mn).
FAU - Legros, J J
AU  - Legros JJ
FAU - Conte-Devolx, B
AU  - Conte-Devolx B
FAU - Rougon-Rapuzzi, G
AU  - Rougon-Rapuzzi G
FAU - Millet, Y
AU  - Millet Y
FAU - Franchimont, P
AU  - Franchimont P
LA  - fre
PT  - Comparative Study
PT  - Journal Article
TT  - Liberation simultanee de vasopressine (A.D.H.) et de neurophysines lors de la 
      perfusion de nicotine chez l'homme.
PL  - France
TA  - C R Seances Soc Biol Fil
JT  - Comptes rendus des seances de la Societe de biologie et de ses filiales
JID - 7505439
RN  - 0 (Neurophysins)
RN  - 11000-17-2 (Vasopressins)
RN  - 6M3C89ZY6R (Nicotine)
SB  - IM
MH  - Humans
MH  - Infusions, Parenteral
MH  - Neurophysins/*metabolism
MH  - Nicotine/*pharmacology
MH  - Pituitary Gland/*drug effects
MH  - Radioimmunoassay
MH  - Vasopressins/*metabolism
EDAT- 1977/01/01 00:00
MHDA- 1977/01/01 00:01
CRDT- 1977/01/01 00:00
PHST- 1977/01/01 00:00 [pubmed]
PHST- 1977/01/01 00:01 [medline]
PHST- 1977/01/01 00:00 [entrez]
PST - ppublish
SO  - C R Seances Soc Biol Fil. 1977;171(2):478-83.