PMID- 1429390
OWN - NLM
STAT- MEDLINE
DCOM- 19921223
LR  - 20190918
IS  - 0277-0903 (Print)
IS  - 0277-0903 (Linking)
VI  - 29
IP  - 6
DP  - 1992
TI  - Airway response to inhaled fenoterol in hyperthyroid patients before and after 
      treatment.
PG  - 369-74
AB  - Bronchodilatory response to inhaled fenoterol was studied in 15 hyperthyroid 
      patients before and after successful treatment with antithyroid drugs. Baseline 
      forced vital capacity (FVC) and forced expiratory volume in 1 sec (FEV1) were 
      lower than the predicted values in 12 and 11 patients, respectively. Improved 
      values were seen after treatment for hyperthyroidism although statistical 
      significance was not reached. Even if some improvement occurred in PEFR (a rise 
      by 0.24-0.48 L/s) and FVC (increase of 73-78 ml) in the hyperthyroid state in 
      response to fenoterol inhalation after various time intervals, the increase in 
      different parameters of lung function was significantly more after the patients 
      achieved euthyroid state (increases in FVC by 290-165 ml; in FEV1 by 333-193 ml; 
      in peak expiratory flow (PEFR) by 0.75-0.52 L/s and in forced expiratory flow 
      (FEF50%) by 0.55-0.31 L/s). In the euthyroid state the mean absolute improvements 
      from the baseline values were significantly higher (< 0.05-0.001). These 
      observations indicate that bronchodilatory response is impaired in the presence 
      of excess thyroid hormones and improves after euthyroid state is achieved.
FAU - Behera, D
AU  - Behera D
AD  - Department of Pulmonary Medicine, Postgraduate Institute of Medical Education and 
      Research, Chandigarh, India.
FAU - Roy, R
AU  - Roy R
FAU - Dash, R J
AU  - Dash RJ
FAU - Jindal, S K
AU  - Jindal SK
LA  - eng
PT  - Journal Article
PL  - England
TA  - J Asthma
JT  - The Journal of asthma : official journal of the Association for the Care of 
      Asthma
JID - 8106454
RN  - 0 (Thyroid Hormones)
RN  - 22M9P70OQ9 (Fenoterol)
SB  - IM
MH  - Administration, Inhalation
MH  - Adult
MH  - Bronchial Hyperreactivity/drug therapy/*physiopathology
MH  - Female
MH  - Fenoterol/*administration & dosage
MH  - Forced Expiratory Volume/physiology
MH  - Humans
MH  - Hyperthyroidism/*drug therapy/*physiopathology
MH  - Male
MH  - Middle Aged
MH  - Respiration/drug effects
MH  - Thyroid Hormones/pharmacology
MH  - Time Factors
EDAT- 1992/01/01 00:00
MHDA- 1992/01/01 00:01
CRDT- 1992/01/01 00:00
PHST- 1992/01/01 00:00 [pubmed]
PHST- 1992/01/01 00:01 [medline]
PHST- 1992/01/01 00:00 [entrez]
AID - 10.3109/02770909209044800 [doi]
PST - ppublish
SO  - J Asthma. 1992;29(6):369-74. doi: 10.3109/02770909209044800.