PMID- 1430323
OWN - NLM
STAT- MEDLINE
DCOM- 19921204
LR  - 20151119
IS  - 0021-9967 (Print)
IS  - 0021-9967 (Linking)
VI  - 323
IP  - 4
DP  - 1992 Sep 22
TI  - Time of origin of cortico-collicular projection neurons in the rat visual cortex.
PG  - 570-6
AB  - The time of origin and the radial gradient of neurogenesis of cortico-collicular 
      neurons have been studied in the rat visual area 17. We used a combined technique 
      for the histochemical detection of the retrogradely transported horseradish 
      peroxidase from the superior colliculus and the autoradiographic detection of the 
      [3H]-thymidine administered during the gestational period. The cortico-collicular 
      neurons of visual area 17 are located in layer V and are generated on gestational 
      day (GD) 15 (59.78%), GD 16 (36.21%), and GD 17 (4.01%). This finding reveals 
      that, for the cortico-collicular neuronal population, the birth date is 
      well-correlated with the laminar position in the adult animal. To see whether the 
      cortico-collicular neurons located at various radial levels of layer V are 
      generated concurrently, or whether they follow an "inside-out" pattern of 
      positioning, we divided layer V into three (upper, middle and lower) sublaminae. 
      Most cortico-collicular neurons located in the lower two-thirds of layer V are 
      generated on GD 15 (65%), whereas the neurons located in the upper third of the 
      layer are generated both on GD 15 and GD 16 in almost equal proportions (52.53% 
      and 44.39%, respectively).
FAU - Contamina, P
AU  - Contamina P
AD  - Departamento de Ciencias Morfologicas, Facultad de Medicina, Universidad de 
      Zaragoza, Spain.
FAU - Boada, E
AU  - Boada E
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Comp Neurol
JT  - The Journal of comparative neurology
JID - 0406041
RN  - EC 1.11.1.- (Horseradish Peroxidase)
RN  - VC2W18DGKR (Thymidine)
SB  - IM
MH  - Animals
MH  - Female
MH  - Histocytochemistry
MH  - Horseradish Peroxidase
MH  - Neurons/*physiology
MH  - Pregnancy
MH  - Rats
MH  - Rats, Wistar
MH  - Superior Colliculi/*physiology
MH  - Thymidine
MH  - Visual Cortex/cytology/growth & development/*physiology
MH  - Visual Pathways/cytology/growth & development/physiology
EDAT- 1992/09/22 00:00
MHDA- 1992/09/22 00:01
CRDT- 1992/09/22 00:00
PHST- 1992/09/22 00:00 [pubmed]
PHST- 1992/09/22 00:01 [medline]
PHST- 1992/09/22 00:00 [entrez]
AID - 10.1002/cne.903230409 [doi]
PST - ppublish
SO  - J Comp Neurol. 1992 Sep 22;323(4):570-6. doi: 10.1002/cne.903230409.