PMID- 1441869
OWN - NLM
STAT- MEDLINE
DCOM- 19921207
LR  - 20190814
IS  - 0001-5172 (Print)
IS  - 0001-5172 (Linking)
VI  - 36
IP  - 7
DP  - 1992 Oct
TI  - Haemodynamic changes associated with thermodilution cardiac output determination 
      during myocardial ischaemia or pulmonary oedema in dogs.
PG  - 679-83
AB  - Since the technique of thermodilution (TD) cardiac output measurements per se 
      causes haemodynamic alterations, the authors examined whether the alterations 
      elicited by iced injectate are augmented in the presence of myocardial ischaemia 
      (MI) or pulmonary oedema (PE), compromised conditions frequently associated with 
      critically ill patients. MI (N = 7) or PE (N = 7) was induced by clamping the 
      anterior descending coronary artery or by a slow infusion of oleic acid into the 
      right atrium, respectively, in anaesthetized dogs. Injection of iced injectate, 3 
      ml, caused similar changes in heart rate, mean systemic and pulmonary arterial 
      pressures, pulmonary blood flow, right ventricular dP/dt, and right atrial 
      pressure in dogs with and without MI or PE. Cardiac output estimated by TD 
      correlated closely with pulmonary blood flow measured by electromagnetic 
      flowmeter in both MI and PE (r > 0.9). No profound alterations in haemodynamics 
      were observed at any injection during TD cardiac output measurements under MI or 
      PE. These results indicate that TD cardiac output determination does not cause 
      serious haemodynamic alterations, and can estimate right ventricular output 
      accurately under MI and PE.
FAU - Nishikawa, T
AU  - Nishikawa T
AD  - Department of Anaesthesiology, Institute of Clinical Medicine, University of 
      Tsukuba, Japan.
FAU - Dohi, S
AU  - Dohi S
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Acta Anaesthesiol Scand
JT  - Acta anaesthesiologica Scandinavica
JID - 0370270
RN  - 142M471B3J (Carbon Dioxide)
SB  - IM
MH  - Animals
MH  - Atrial Function, Right/physiology
MH  - Blood Pressure/physiology
MH  - Carbon Dioxide/blood
MH  - Cardiac Output/*physiology
MH  - Dogs
MH  - Electromagnetic Phenomena
MH  - Female
MH  - Heart Rate/physiology
MH  - Hemodynamics
MH  - Male
MH  - Myocardial Ischemia/*physiopathology
MH  - Pulmonary Artery/physiology
MH  - Pulmonary Circulation/physiology
MH  - Pulmonary Edema/blood/*physiopathology
MH  - Stroke Volume/physiology
MH  - Thermodilution
MH  - Ventricular Function, Right/physiology
EDAT- 1992/10/01 00:00
MHDA- 1992/10/01 00:01
CRDT- 1992/10/01 00:00
PHST- 1992/10/01 00:00 [pubmed]
PHST- 1992/10/01 00:01 [medline]
PHST- 1992/10/01 00:00 [entrez]
AID - 10.1111/j.1399-6576.1992.tb03543.x [doi]
PST - ppublish
SO  - Acta Anaesthesiol Scand. 1992 Oct;36(7):679-83. doi: 
      10.1111/j.1399-6576.1992.tb03543.x.