PMID- 14503368
OWN - NLM
STAT- MEDLINE
DCOM- 20031212
LR  - 20140625
VI  - 17
IP  - 6
DP  - 2003 Jun
TI  - [Investigation on recurrent-associated gene expression pattern of 
      recurrent-laryngeal squamous cell carcinoma].
PG  - 339-41
AB  - OBJECTIVE: To screen out recurrent-associated gene in expression pattern of 
      laryngeal squamous cell carcinoma(LSCC). METHOD: By cDNA array chip containing 
      18,000 gene, the gene expression pattern of cancer and normal mucosal tissues in 
      2 cases of LSCC, were compared and analyzed. RESULT: 1. 218 genes expressed 
      repeatedly and differentially in LSCC were discovery. Among these genes, up- and 
      down-regulated were 137 and 81; 2. The genes whose expression difference was over 
      10 times were U02570, AW863712, AA523939 and NM_014381. CONCLUSION: The episode 
      of recurrent LSCC was a process of disturbance of numerous gene expression. 
      GTPase activating protein (U02570) and DNA mismatch repair gene(NM_014381) 
      probably played a major role in the episode.
FAU - Wang, Binquan
AU  - Wang B
AD  - Department of Otorhinolaryngology, First Hospital of Shanxi Medical University, 
      Taiyuan 030001.
FAU - Chen, Yanqiu
AU  - Chen Y
FAU - Wen, Shuxin
AU  - Wen S
FAU - Xia, Lijun
AU  - Xia L
FAU - Wang, Jianming
AU  - Wang J
FAU - Huangfu, Hui
AU  - Huangfu H
FAU - Gong, Jialei
AU  - Gong J
FAU - He, Xianfeng
AU  - He X
LA  - chi
PT  - English Abstract
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Lin Chuang Er Bi Yan Hou Ke Za Zhi
JT  - Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology
JID - 9426080
RN  - 0 (RNA, Messenger)
SB  - IM
MH  - Aged
MH  - Carcinoma, Squamous Cell/*genetics
MH  - Gene Expression Profiling
MH  - Gene Expression Regulation, Neoplastic
MH  - Humans
MH  - Laryngeal Neoplasms/*genetics
MH  - Male
MH  - Middle Aged
MH  - Neoplasm Recurrence, Local/*genetics
MH  - RNA, Messenger/genetics
EDAT- 2003/09/25 05:00
MHDA- 2003/12/13 05:00
CRDT- 2003/09/25 05:00
PHST- 2003/09/25 05:00 [pubmed]
PHST- 2003/12/13 05:00 [medline]
PHST- 2003/09/25 05:00 [entrez]
PST - ppublish
SO  - Lin Chuang Er Bi Yan Hou Ke Za Zhi. 2003 Jun;17(6):339-41.