PMID- 14515729 OWN - NLM STAT- MEDLINE DCOM- 20031125 LR - 20110727 IS - 0047-1852 (Print) IS - 0047-1852 (Linking) VI - 61 IP - 9 DP - 2003 Sep TI - [Adult T cell leukemia/lymphoma (ATL)]. PG - 1592-5 AB - Adult T cell leukemia/lymphoma(ATL) is an aggressive, fatal malignancy associated with human T-lymphotropic virus type I(HTLV-I). The median survival time of acute- and lymphoma-type ATL is 6 and 10 months, respectively. According to recent reports, nearly half of the ATL patients who received allogeneic hematopoietic stem cell transplantation could survive without disease for over 3 years. However, the population of patients who are eligible for conventional transplantation is extremely limited. Therefore, a reduced-intensity allogeneic stem cell transplantation(RIST) is applied to ATL patients and a multi-center phase I clinical trial is now underway. In our institute, 5 patients, who received RIST, are all alive, with 1 case relapsed after 6 months. Thus, RIST is considered very promising. FAU - Tanosaki, Ryuji AU - Tanosaki R AD - Division of Laboratory Medicine, National Cancer Center Hospital. LA - jpn PT - Case Reports PT - English Abstract PT - Journal Article PT - Review PL - Japan TA - Nihon Rinsho JT - Nihon rinsho. Japanese journal of clinical medicine JID - 0420546 SB - IM MH - Animals MH - Clinical Trials, Phase I as Topic MH - *Hematopoietic Stem Cell Transplantation MH - Humans MH - Leukemia-Lymphoma, Adult T-Cell/*therapy MH - Male MH - Middle Aged MH - Transplantation Conditioning/methods MH - Transplantation, Homologous RF - 6 EDAT- 2003/10/01 05:00 MHDA- 2003/12/03 05:00 CRDT- 2003/10/01 05:00 PHST- 2003/10/01 05:00 [pubmed] PHST- 2003/12/03 05:00 [medline] PHST- 2003/10/01 05:00 [entrez] PST - ppublish SO - Nihon Rinsho. 2003 Sep;61(9):1592-5.