PMID- 1451842
OWN - NLM
STAT- MEDLINE
DCOM- 19930104
LR  - 20131121
IS  - 0011-7781 (Print)
IS  - 0011-7781 (Linking)
VI  - 64
IP  - 11
DP  - 1992 Nov
TI  - The prehospital use of nebulized albuterol on patients with wheezing whose chief 
      complaint is shortness of breath.
PG  - 679-83
AB  - The use of prehospital nebulized beta-agonists has become widespread, and their 
      safety and efficacy has been documented. Our purpose was to study their broadened 
      use and determine their effectiveness in specific sub-sets of wheezing patients. 
      We conducted a six and one-half month prospective study to determine the benefit 
      of nebulized albuterol treatments on a variety of wheezing patients whose chief 
      complaint to paramedics was shortness of breath. Sixty-two patients were enrolled 
      in the study and were subdivided into four groups based on patient history; 
      asthma, COPD, asthma & COPD (A/C), and non-Asthma/non-COPD (NANC). The 
      effectiveness of the treatment was evaluated objectively by peak expiratory flow 
      rates (PEFR) obtained before and immediately after treatment and subjectively by 
      the patients' evaluation of their own dyspnea. Changes in PEFR were subjected to 
      analysis by a paired T-test. Albuterol was effective in increasing the PEFR in 
      patients with asthma, COPD and NANC. Patients with both asthma and COPD did not 
      demonstrate increased PEFR after treatment. The majority of all patients were 
      subjectively improved after nebulized albuterol treatments. We conclude that 
      aerosolized albuterol is safe and effective in the prehospital treatment of 
      patients complaining of dyspnea who are wheezing.
FAU - Dickinson, E T
AU  - Dickinson ET
AD  - Albany Medical College, NY.
FAU - O'Connor, R E
AU  - O'Connor RE
FAU - Megargel, R
AU  - Megargel R
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Del Med J
JT  - Delaware medical journal
JID - 0370077
RN  - QF8SVZ843E (Albuterol)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Albuterol/*administration & dosage
MH  - Asthma/complications/*drug therapy
MH  - Child
MH  - Child, Preschool
MH  - Emergency Medical Services
MH  - Female
MH  - Humans
MH  - Lung Diseases, Obstructive/complications/*drug therapy
MH  - Male
MH  - Middle Aged
MH  - Nebulizers and Vaporizers
MH  - Prospective Studies
MH  - Respiratory Sounds/*etiology
EDAT- 1992/11/01 00:00
MHDA- 1992/11/01 00:01
CRDT- 1992/11/01 00:00
PHST- 1992/11/01 00:00 [pubmed]
PHST- 1992/11/01 00:01 [medline]
PHST- 1992/11/01 00:00 [entrez]
PST - ppublish
SO  - Del Med J. 1992 Nov;64(11):679-83.