PMID- 1452948 OWN - NLM STAT- MEDLINE DCOM- 19930107 LR - 20190907 IS - 0731-5724 (Print) IS - 0731-5724 (Linking) VI - 11 IP - 5 DP - 1992 Oct TI - Plasma amino acid responses of trained athletes to two successive exhaustion trials with and without interim carbohydrate feeding. PG - 501-11 AB - The purpose of this research was to measure changes in selected plasma amino acids (AA) during two successive exercise trials to exhaustion. Eleven trained male athletes completed these trials at weeks 4, 6, 8 and 12. Blood samples for each test were collected after a 12-hour fast at times (in minutes) 0 (Resting), 45, 90, 135, 180, at exhaustion (EI), after a 20-minute recovery period, and at the second exhaustion (EII). At the end of EI, subjects consumed an artificially sweetened water replacement (placebo) treatment or a carbohydrate (CHO) replacement (1.1 g CHO/kg BW) in order to determine any effect of CHO replacement on changes in energy substrates or AA, adjusted for plasma volume changes. From baseline to EI, alpha-aminobutyric acid, alanine, glycine, isoleucine, serine, valine threonine, and tyrosine decreased significantly (p less than or equal to 0.05), while taurine increased significantly. During the recovery period following EI, isoleucine, leucine, ornithine, phenylalanine, tyrosine, urea and valine increased significantly. From the end of recovery until EII, alanine, aspartic acid, glycine, isoleucine, leucine, ornithine, phenylalanine, serine, threonine, tyrosine and valine decreased significantly. CHO replacement had no effect on the mean change scores for any AA from EI to the end of the recovery period and affected only serine, citrulline, glycine and threonine from the end of the recovery period to EII. FAU - Bazzarre, T L AU - Bazzarre TL AD - Department of Nutrition, University of North Carolina-Greensboro. FAU - Murdoch, S D AU - Murdoch SD FAU - Wu, S M AU - Wu SM FAU - Herr, D G AU - Herr DG FAU - Snider, I P AU - Snider IP LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - J Am Coll Nutr JT - Journal of the American College of Nutrition JID - 8215879 RN - 0 (Amino Acids) RN - 0 (Blood Glucose) RN - 0 (Dietary Carbohydrates) RN - 0 (Fatty Acids) RN - 0 (Lactates) RN - 33X04XA5AT (Lactic Acid) SB - IM MH - Adolescent MH - Adult MH - Amino Acids/*blood MH - Blood Glucose/analysis MH - Dietary Carbohydrates/*pharmacology MH - Fatty Acids/blood MH - Humans MH - Lactates/blood MH - Lactic Acid MH - Male MH - Physical Exertion/*physiology MH - Rest/physiology EDAT- 1992/10/01 00:00 MHDA- 1992/10/01 00:01 CRDT- 1992/10/01 00:00 PHST- 1992/10/01 00:00 [pubmed] PHST- 1992/10/01 00:01 [medline] PHST- 1992/10/01 00:00 [entrez] AID - 10.1080/07315724.1992.10718254 [doi] PST - ppublish SO - J Am Coll Nutr. 1992 Oct;11(5):501-11. doi: 10.1080/07315724.1992.10718254.