PMID- 14550736
OWN - NLM
STAT- MEDLINE
DCOM- 20031218
LR  - 20220410
IS  - 1090-0233 (Print)
IS  - 1090-0233 (Linking)
VI  - 166
IP  - 3
DP  - 2003 Nov
TI  - Association of porcine circovirus 2 with porcine respiratory disease complex.
PG  - 251-6
AB  - A retrospective study was performed on natural cases of porcine respiratory 
      disease complex (PRDC) to determine the association and prevalence of PRDC with 
      porcine circovirus 2 (PCV2) and other co-existing pathogens in Korea. 
      Histologically, alveolar septa were markedly thickened by infiltrates of 
      mononuclear cells. Moderate to marked multifocal peribronchial and 
      peribronchiolar fibrosis were present and often extended into the airway lamina 
      propria. Among the 105 pigs with PRDC, 85 were positive for PCV2, 66 were 
      positive for porcine reproductive and respiratory syndrome virus (PRRSV), 60 were 
      positive for porcine parvovirus (PPV), and 14 were positive for swine influenza 
      virus (SIV). There were 80 co-infections and 25 single infections. A co-infection 
      of PCV2 with another additional bacterial pathogen is frequently diagnosed in 
      PRDC. The combination of PCV2 and Pasteurella multocida (38 cases) was most 
      prevalent followed by PCV2 and Mycoplasma hyopneumoniae (33 cases). The 
      consistent presence of PCV2, but lower prevalence of other viral and bacterial 
      pathogens in all pigs examined with PRDC, has led us to speculate that PCV2 plays 
      an important role in PRDC.
FAU - Kim, J
AU  - Kim J
AD  - Department of Veterinary Pathology, College of Veterinary Medicine, Seoul 
      National University, Suwon 441-744, Kyounggi-Do, Republic of Korea.
FAU - Chung, H-K
AU  - Chung HK
FAU - Chae, C
AU  - Chae C
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Vet J
JT  - Veterinary journal (London, England : 1997)
JID - 9706281
SB  - IM
CIN - Vet J. 2003 Nov;166(3):222-3. PMID: 14550730
MH  - Animals
MH  - Circoviridae Infections/epidemiology/*veterinary/virology
MH  - Circovirus/genetics/*growth & development
MH  - Korea/epidemiology
MH  - Respiratory Tract Diseases/epidemiology/*veterinary/virology
MH  - Retrospective Studies
MH  - Swine
MH  - Swine Diseases/epidemiology/*virology
EDAT- 2003/10/11 05:00
MHDA- 2003/12/19 05:00
CRDT- 2003/10/11 05:00
PHST- 2003/10/11 05:00 [pubmed]
PHST- 2003/12/19 05:00 [medline]
PHST- 2003/10/11 05:00 [entrez]
AID - S1090023302002575 [pii]
AID - 10.1016/s1090-0233(02)00257-5 [doi]
PST - ppublish
SO  - Vet J. 2003 Nov;166(3):251-6. doi: 10.1016/s1090-0233(02)00257-5.