PMID- 14568313
OWN - NLM
STAT- MEDLINE
DCOM- 20031209
LR  - 20190712
IS  - 0031-9384 (Print)
IS  - 0031-9384 (Linking)
VI  - 80
IP  - 1
DP  - 2003 Oct
TI  - Forebrain c-fos expression under conditions conducive to pair bonding in female 
      prairie voles (Microtus ochrogaster).
PG  - 95-101
AB  - Repeated mating over a period of 6 h facilitates pair-bond formation in 
      monogamous prairie voles. Using this paradigm, we examined fos expression in 
      brain areas implicated in social behavior in voles. We hypothesized that the 
      presence of the fos protein after a period of time sufficient for pair bonding to 
      occur may indicate brain areas that are especially important in pair bond 
      formation. We found elevated levels of fos immunoreactivity in the medial and 
      cortical amygdala, medial preoptic area (MPOA), and bed nucleus of the stria 
      terminalis (BNST) in females that mated several times over a 6-h period as 
      compared to a variety of unmated controls. No treatment effects were found in the 
      central amygdala, nucleus accumbens (NAcc), or lateral septum (LS). We suggest 
      that areas that show evidence of fos expression after sufficient time for pair 
      bonding to occur may be important in the formation of associations between the 
      partner and mating stimuli.
FAU - Curtis, J Thomas
AU  - Curtis JT
AD  - Department of Psychology and Neuroscience Program, Florida State University, 209 
      Copeland Avenue, Tallahassee, FL 32306, USA. tcurtis@psy.fsu.edu
FAU - Wang, Zuoxin
AU  - Wang Z
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - Physiol Behav
JT  - Physiology & behavior
JID - 0151504
RN  - 0 (Proto-Oncogene Proteins c-fos)
SB  - IM
MH  - Amygdala/metabolism
MH  - Animals
MH  - Arvicolinae/*metabolism
MH  - *Brain Mapping
MH  - Female
MH  - Nucleus Accumbens/metabolism
MH  - *Pair Bond
MH  - Preoptic Area/metabolism
MH  - Prosencephalon/*metabolism
MH  - Proto-Oncogene Proteins c-fos/*metabolism
MH  - Septal Nuclei/metabolism
MH  - Septum of Brain/metabolism
MH  - Sexual Behavior, Animal/*physiology
EDAT- 2003/10/22 05:00
MHDA- 2003/12/10 05:00
CRDT- 2003/10/22 05:00
PHST- 2003/10/22 05:00 [pubmed]
PHST- 2003/12/10 05:00 [medline]
PHST- 2003/10/22 05:00 [entrez]
AID - S0031938403002269 [pii]
AID - 10.1016/s0031-9384(03)00226-9 [doi]
PST - ppublish
SO  - Physiol Behav. 2003 Oct;80(1):95-101. doi: 10.1016/s0031-9384(03)00226-9.