PMID- 14574164
OWN - NLM
STAT- MEDLINE
DCOM- 20031216
LR  - 20191108
IS  - 1389-9600 (Print)
IS  - 1389-9600 (Linking)
VI  - 2
IP  - 1
DP  - 2003
TI  - Quality of life in patients with multiple endocrine neoplasia type 1 (MEN 1).
PG  - 27-33
AB  - To study quality of life among patients living with a hereditary tumor syndrome, 
      the small group with multiple endocrine neoplasia type 1 (MEN1) was selected. It 
      is characterized by multifocal adenomas of the pancreas, parathyroid, anterior 
      pituitary and other endocrine glands. Patients were assessed at an in-hospital 
      stay and six months later at home. Patients at a specialist ward for MEN1 were 
      recruited consecutively (n = 36) during one year. Eighty-one percent participated 
      (n = 29). Four questionnaires were used: the Hospital Anxiety and Depression 
      Scale (HADS), the Impact of Event Scale (IES), the Life Orientation Test (LOT) 
      and the Short Form-36 (SF-36). Psychosocial outcome measures (anxiety, 
      depression, intrusion, avoidance) changed only marginally between the in hospital 
      stay and six months later at home. However, depression increased for patients 
      categorized as having a high burden of disease and treatment. Compared to 
      population-based norm values, the SF-36 scores of the patient group MEN1were 
      lower for General Health and Social Functioning. Optimism assessed at the 
      hospital was a predictor of Mental Health six months later. Most MEN 1 patients 
      (70%) were pessimists. Patients having a higher burden of disease and treatment 
      are in need of support after discharge. Patients could easily be monitored with 
      questionnaires and, when indicated, offered help for their psychosocial distress.
FAU - Berglund, G
AU  - Berglund G
AD  - Department of Public Health and Caring Sciences, Uppsala University, Uppsala 
      Science Park, S-751 83, Uppsala, Sweden. gunilla.berglund@pubcare.uu.se
FAU - Liden, A
AU  - Liden A
FAU - Hansson, M G
AU  - Hansson MG
FAU - Oberg, K
AU  - Oberg K
FAU - Sjoden, P O
AU  - Sjoden PO
FAU - Nordin, K
AU  - Nordin K
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - Fam Cancer
JT  - Familial cancer
JID - 100898211
SB  - IM
EIN - Fam Cancer. 2003;2(2):151
MH  - Adult
MH  - Aged
MH  - Anxiety
MH  - *Cost of Illness
MH  - Depression/*etiology
MH  - Female
MH  - Health Status
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Multiple Endocrine Neoplasia Type 1/*complications/*psychology
MH  - Prospective Studies
MH  - *Quality of Life
MH  - Social Support
MH  - Stress, Psychological
MH  - *Surveys and Questionnaires
EDAT- 2003/10/24 05:00
MHDA- 2003/12/17 05:00
CRDT- 2003/10/24 05:00
PHST- 2003/10/24 05:00 [pubmed]
PHST- 2003/12/17 05:00 [medline]
PHST- 2003/10/24 05:00 [entrez]
AID - 5113101 [pii]
AID - 10.1023/a:1023252107120 [doi]
PST - ppublish
SO  - Fam Cancer. 2003;2(1):27-33. doi: 10.1023/a:1023252107120.