PMID- 14609306 OWN - NLM STAT- MEDLINE DCOM- 20040311 LR - 20170511 IS - 0001-5385 (Print) IS - 0001-5385 (Linking) VI - 58 IP - 5 DP - 2003 Oct TI - Influence of commissural calcification on the immediate outcomes of percutaneous balloon mitral valvuloplasty. PG - 411-5 AB - OBJECTIVES: To evaluate the impact of mild to moderate commissural calcification on the immediate outcomes of percutaneous balloon mitral valvuloplasty (PBMV). METHODS AND RESULTS: We analysed the results of 223 consecutive patients (mean age 37.6 +/- 8.7 years) who underwent PBMV for rheumatic mitral stenosis. Commissural calcification was identified with a two-dimensional echocardiography (echo) in 65 (29.1%) patients with the severity of calcification being graded from 0-3. The anatomy and function of the mitral valve were assessed byWilkins echo score. In patients with no commissural calcification the increase in mitral valve area after PBMV was 0.90 +/- 0.42 cm2, which was greater than the increase in those with calcification grade 1 (0.83 +/- 0.42 cm2, p < 0.05), grade 2 (0.72 +/- 0.38 cm2, p < 0.05) and grade 3 (0.63 +/- 0.13 cm2, p < 0.05). In patients with an echo score of < or = 8, the presence of commissural calcification was associated with a smaller increase in mitral valve area (p < 0.05) and a smaller reduction in New York Heart Association (NYHA) function class after PBMV (p < 0.05). In patients with an echo score of more than 8, commissural calcification had no significant effect on the valve area increase and NYHA function class reduction (p > 0.05). CONCLUSIONS: Commissural calcification has an adverse effect on the clinical results of PBMV. Detailed pre-procedural assessment of commissural calcification with echocardiography must be performed to provide background information on the immediate outcomes of PBMV. FAU - Wei, Tiemin AU - Wei T AD - Department of Cardiology, Lishui City Central Hospital, Zhejiang Province, People's Republic of China. FAU - Zeng, Chunlai AU - Zeng C FAU - Chen, Fanghong AU - Chen F FAU - Wang, Chunming AU - Wang C FAU - Chen, Liping AU - Chen L FAU - Chen, Qunying AU - Chen Q FAU - Lan, Wenshenh AU - Lan W FAU - Wang, Lexin AU - Wang L LA - eng PT - Journal Article PL - England TA - Acta Cardiol JT - Acta cardiologica JID - 0370570 SB - IM MH - Adolescent MH - Adult MH - Aged MH - Analysis of Variance MH - Calcinosis/complications/diagnostic imaging/*surgery MH - *Catheterization MH - Echocardiography MH - Female MH - Humans MH - Male MH - Middle Aged MH - Mitral Valve Stenosis/complications/diagnostic imaging/*surgery MH - Rheumatic Heart Disease/complications/diagnostic imaging/*surgery MH - Treatment Outcome EDAT- 2003/11/12 05:00 MHDA- 2004/03/12 05:00 CRDT- 2003/11/12 05:00 PHST- 2003/11/12 05:00 [pubmed] PHST- 2004/03/12 05:00 [medline] PHST- 2003/11/12 05:00 [entrez] AID - 10.2143/AC.58.5.2005305 [doi] PST - ppublish SO - Acta Cardiol. 2003 Oct;58(5):411-5. doi: 10.2143/AC.58.5.2005305.