PMID- 14613228 OWN - NLM STAT- MEDLINE DCOM- 20040914 LR - 20131121 IS - 1549-3296 (Print) IS - 1549-3296 (Linking) VI - 67 IP - 3 DP - 2003 Dec 1 TI - Hydroxyapatite whiskers provide improved mechanical properties in reinforced polymer composites. PG - 801-12 AB - Synthetic hydroxyapatite (HA) whiskers have been utilized as a new, biocompatible reinforcement for orthopedic biomaterials. High-density polyethylene (HDPE) was reinforced with either the synthesized HA whiskers or a commercially available spherical HA powder using a novel powder processing technique that facilitated uniform dispersion of the reinforcements in the matrix prior to compression molding. Composites were processed for up to 60 vol % HA whiskers and up to 50 vol % spherical HA. The mechanical properties of the new composite biomaterials were examined by uniaxial tensile tests. As expected, increased volume fraction of either reinforcement type over 0-50 vol % resulted in increased elastic modulus, a maximum in ultimate tensile stress, and decreased work to failure. Composites reinforced with HA whiskers had higher elastic modulus, ultimate tensile strength, and work to failure relative to composites reinforced with spherical HA. Thus, HA whisker-reinforced HDPE composites possessed improved mechanical properties over those reinforced with spherical HA. HA whisker-reinforced composites were anisotropic due to alignment of the whiskers in the matrix during processing. CI - Copyright 2003 Wiley Periodicals, Inc. J Biomed Mater Res 67A: 801-812, 2003 FAU - Roeder, Ryan K AU - Roeder RK AD - Department of Aerospace and Mechanical Engineering, University of Notre Dame, 381 Fitzpatrick Hall, Notre Dame, IN 46556-5637, USA. rroeder@nd.edu FAU - Sproul, Michael M AU - Sproul MM FAU - Turner, Charles H AU - Turner CH LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - J Biomed Mater Res A JT - Journal of biomedical materials research. Part A JID - 101234237 RN - 0 (Biocompatible Materials) RN - 0 (Composite Resins) RN - 9002-88-4 (Polyethylene) RN - 91D9GV0Z28 (Durapatite) SB - IM MH - Biocompatible Materials/chemical synthesis/pharmacology/*standards MH - Biomechanical Phenomena MH - Composite Resins/chemical synthesis/*pharmacology MH - Durapatite/chemical synthesis/*pharmacology MH - Materials Testing MH - Polyethylene/pharmacology MH - Surface Properties EDAT- 2003/11/13 05:00 MHDA- 2004/09/15 05:00 CRDT- 2003/11/13 05:00 PHST- 2003/11/13 05:00 [pubmed] PHST- 2004/09/15 05:00 [medline] PHST- 2003/11/13 05:00 [entrez] AID - 10.1002/jbm.a.10140 [doi] PST - ppublish SO - J Biomed Mater Res A. 2003 Dec 1;67(3):801-12. doi: 10.1002/jbm.a.10140.