PMID- 14616094
OWN - NLM
STAT- MEDLINE
DCOM- 20040414
LR  - 20190823
IS  - 0105-4538 (Print)
IS  - 0105-4538 (Linking)
VI  - 58
IP  - 12
DP  - 2003 Dec
TI  - Future therapeutic options in food allergy.
PG  - 1217-23
AB  - Up to 5% of young children and 2% of adults suffer from food allergy. Among them 
      many have immunoglobulin E (IgE)-mediated food allergy, a condition with 
      potentially fatal allergic reactions. Several studies have addressed possible 
      definite treatment options for food allergy. Immunotherapy, by the oral route or 
      by systemic injections shows promising preliminary results, but current 
      interpretation of these therapeutic options are mostly handicapped by studies 
      with insufficient scientific support, or by severe side-effects. Currently, no 
      studies can support pharmacotherapy. Finally, most promising results were 
      recently published with anti-IgE antibodies in a human trial, or various 
      approaches in a mouse model of food allergy (chinese herbal medicine, specific 
      modulation of the T cell response). Rapidly evolving findings might provide hope 
      for a cure of food allergy in the near future.
FAU - Eigenmann, P A
AU  - Eigenmann PA
AD  - Department of Pediatrics, University Hospital of Geneva, Geneva, Switzerland.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - Denmark
TA  - Allergy
JT  - Allergy
JID - 7804028
SB  - IM
MH  - Adult
MH  - Animals
MH  - Child
MH  - Dogs
MH  - Food Hypersensitivity/*immunology/*therapy
MH  - Humans
MH  - Immunotherapy/methods/*trends
MH  - Mice
MH  - Models, Animal
MH  - Rats
RF  - 48
EDAT- 2003/11/18 05:00
MHDA- 2004/04/15 05:00
CRDT- 2003/11/18 05:00
PHST- 2003/11/18 05:00 [pubmed]
PHST- 2004/04/15 05:00 [medline]
PHST- 2003/11/18 05:00 [entrez]
AID - 303 [pii]
AID - 10.1046/j.1398-9995.2003.00303.x [doi]
PST - ppublish
SO  - Allergy. 2003 Dec;58(12):1217-23. doi: 10.1046/j.1398-9995.2003.00303.x.