PMID- 1462851
OWN - NLM
STAT- MEDLINE
DCOM- 19930113
LR  - 20141120
IS  - 0379-0363 (Print)
IS  - 0379-0363 (Linking)
VI  - 38 ( Pt 3)
DP  - 1992
TI  - Vascular wall kininogen concentration is inversely related to intrinsic 
      kininogenase in spontaneously hypertensive rats.
PG  - 10-3
AB  - We determined kininogen concentration and kininogenase activity in the 
      blood-free, aorta homogenates of 15 week old spontaneously hypertensive rats 
      (SHR) and in their age-matched wistar kyoto (WKY) controls. Active kininogenase 
      in the SHR was only 18% of the WKY controls. Thus, the kininogen concentration 
      was inversely related to kininogenase activity suggesting a local interaction of 
      these components and possible generation of kinins within the vascular wall.
FAU - Oza, N B
AU  - Oza NB
AD  - Evans Memorial Department of Clinical Research, University Hospital, Boston 
      University School of Medicine, MA 02118.
FAU - Goud, H D
AU  - Goud HD
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - Switzerland
TA  - Agents Actions Suppl
JT  - Agents and actions. Supplements
JID - 7801014
RN  - 0 (Kininogens)
RN  - 0 (Kinins)
RN  - EC 3.4.21.- (Kallikreins)
SB  - IM
MH  - Animals
MH  - Aorta/*metabolism
MH  - Blood Pressure
MH  - In Vitro Techniques
MH  - Kallikreins/*metabolism
MH  - Kininogens/*metabolism
MH  - Kinins/analysis
MH  - Muscle, Smooth, Vascular/*metabolism
MH  - Radioimmunoassay
MH  - Rats
MH  - Rats, Inbred SHR
MH  - Rats, Inbred WKY
EDAT- 1992/01/01 00:00
MHDA- 1992/01/01 00:01
CRDT- 1992/01/01 00:00
PHST- 1992/01/01 00:00 [pubmed]
PHST- 1992/01/01 00:01 [medline]
PHST- 1992/01/01 00:00 [entrez]
PST - ppublish
SO  - Agents Actions Suppl. 1992;38 ( Pt 3):10-3.