PMID- 14641116
OWN - NLM
STAT- MEDLINE
DCOM- 20040324
LR  - 20190721
IS  - 0105-1873 (Print)
IS  - 0105-1873 (Linking)
VI  - 49
IP  - 1
DP  - 2003 Jul
TI  - Specific immunoglobulin E in patients with immediate persulfate hypersensitivity.
PG  - 22-5
AB  - Persulfate salts may cause contact urticaria, allergic and irritant contact 
      dermatitis, rhinitis and asthma. The mechanism of the immediate reactions has 
      been unclear. Positive prick test, skin application and nasal and bronchial 
      provocations identify immediate allergy. There is only 1 previous report of 
      specific binding of immunoglobulin E (IgE) to ammonium persulfate demonstrated by 
      radioallergosorbent test (RAST). In the present study, fresh 2% ammonium and 
      potassium persulfate solutions were used for prick testing. Patients with 
      positive prick tests were further evaluated with open skin application, 
      immunospot and RAST. Prick testing with persulfate salts was performed in a total 
      of 138 patients. 7 patients had a positive reaction to at least 1 persulfate 
      salt. 6 of the patients had had skin symptoms, urticaria, eczema or angioedema, 
      because of contact with hair bleaches. Open application on healthy skin was 
      performed in 4 patients, and 3 out of them had urticarial reactions. The sera of 
      5 patients were investigated with immunospot and RAST. On immunospot, specific 
      binding of IgE to human serum albumin (HSA)-conjugated ammonium and potassium 
      persulfate was found in 2 patients. 1 immunospot-positive patient also had a 
      positive RAST to ammonium persulfate-HSA conjugate. The mechanism of immediate 
      hypersensitivity to persulfates thus seems to be IgE-mediated at least in some 
      patients.
FAU - Aalto-Korte, Kristiina
AU  - Aalto-Korte K
AD  - Division of Dermatology and Venereology, Helsinki University Central Hospital, 
      Skin and Allergy Hospital, Helsinki, Finland. kristina.aalto.korte@ttl.fi
FAU - Makinen-Kiljunen, Soili
AU  - Makinen-Kiljunen S
LA  - eng
PT  - Journal Article
PL  - England
TA  - Contact Dermatitis
JT  - Contact dermatitis
JID - 7604950
RN  - 0 (Hair Preparations)
RN  - 0 (Potassium Compounds)
RN  - 0 (Sulfates)
RN  - 22QF6L357F (ammonium peroxydisulfate)
RN  - 37341-29-0 (Immunoglobulin E)
RN  - 6B86K0MCZC (potassium persulfate)
RN  - SU46BAM238 (Ammonium Sulfate)
SB  - IM
MH  - Adult
MH  - Ammonium Sulfate/adverse effects/immunology
MH  - Dermatitis, Allergic Contact/etiology/*immunology
MH  - Dermatitis, Occupational/etiology/immunology
MH  - Enzyme-Linked Immunosorbent Assay
MH  - Female
MH  - Hair Preparations/adverse effects
MH  - Humans
MH  - Immunoglobulin E/*metabolism
MH  - Male
MH  - Middle Aged
MH  - Potassium Compounds/adverse effects/immunology
MH  - Radioallergosorbent Test
MH  - Sulfates/adverse effects/*immunology
MH  - Urticaria/etiology/*immunology
EDAT- 2003/12/04 05:00
MHDA- 2004/03/25 05:00
CRDT- 2003/12/04 05:00
PHST- 2003/12/04 05:00 [pubmed]
PHST- 2004/03/25 05:00 [medline]
PHST- 2003/12/04 05:00 [entrez]
AID - 134 [pii]
AID - 10.1111/j.0105-1873.2003.00134.x [doi]
PST - ppublish
SO  - Contact Dermatitis. 2003 Jul;49(1):22-5. doi: 10.1111/j.0105-1873.2003.00134.x.