PMID- 14648169
OWN - NLM
STAT- MEDLINE
DCOM- 20041022
LR  - 20181113
IS  - 0009-5915 (Print)
IS  - 0009-5915 (Linking)
VI  - 112
IP  - 5
DP  - 2004 Feb
TI  - Characterization of ancestral chromosome fusion points in the Indian muntjac 
      deer.
PG  - 213-20
AB  - Tandem fusion, a rare evolutionary chromosome rearrangement, has occurred 
      extensively in muntjac karyotypic evolution, leading to an extreme fusion 
      karyotype of 6/7 (female/male) chromosomes in the Indian muntjac. These fusion 
      chromosomes contain numerous ancestral chromosomal break and fusion points. Here, 
      we designed a composite polymerase chain reaction (PCR) strategy which recovered 
      DNA fragments that contained telomere and muntjac satellite DNA sequence repeats. 
      Nested PCR confirmed the specificity of the products. Two-color fluorescence in 
      situ hybridization (FISH) with the repetitive sequences obtained and T2AG3 
      telomere probes showed co-localization of satellite and telomere sequences in 
      Indian muntjac chromosomes. Adjacent telomere and muntjac satellite sequences 
      were also seen by fiber FISH. These data lend support to the involvement of 
      telomere and GC-rich satellite DNA sequences during muntjac chromosome fusions.
FAU - Hartmann, Nils
AU  - Hartmann N
AD  - Max-Planck-Institut fur Molekulare Genetik, Ihnestrasse 73, 14195 Berlin, 
      Germany.
FAU - Scherthan, Harry
AU  - Scherthan H
LA  - eng
SI  - GENBANK/AY322158
SI  - GENBANK/AY322159
SI  - GENBANK/AY322160
PT  - Journal Article
DEP - 20031126
PL  - Austria
TA  - Chromosoma
JT  - Chromosoma
JID - 2985138R
RN  - 0 (DNA Probes)
RN  - 0 (DNA, Satellite)
SB  - IM
MH  - Animals
MH  - Chromosome Banding
MH  - Chromosome Breakage/*genetics
MH  - Chromosome Mapping
MH  - Chromosomes/*genetics
MH  - DNA Probes
MH  - DNA, Satellite/*genetics
MH  - Female
MH  - In Situ Hybridization, Fluorescence
MH  - Male
MH  - Molecular Sequence Data
MH  - Muntjacs/*genetics
MH  - Sequence Alignment
MH  - Sequence Homology, Nucleic Acid
MH  - Telomere/*genetics
EDAT- 2003/12/03 05:00
MHDA- 2004/10/23 09:00
CRDT- 2003/12/03 05:00
PHST- 2003/06/23 00:00 [received]
PHST- 2003/09/23 00:00 [revised]
PHST- 2003/09/25 00:00 [accepted]
PHST- 2003/12/03 05:00 [pubmed]
PHST- 2004/10/23 09:00 [medline]
PHST- 2003/12/03 05:00 [entrez]
AID - 10.1007/s00412-003-0262-4 [doi]
PST - ppublish
SO  - Chromosoma. 2004 Feb;112(5):213-20. doi: 10.1007/s00412-003-0262-4. Epub 2003 Nov 
      26.