PMID- 14662449
OWN - NLM
STAT- MEDLINE
DCOM- 20040108
LR  - 20191210
IS  - 0077-8923 (Print)
IS  - 0077-8923 (Linking)
VI  - 1004
DP  - 2003 Oct
TI  - Adaptation of saccadic eye movements: transfer and specificity.
PG  - 69-77
AB  - The present study was designed to test whether the adaptation of saccadic eye 
      movements depends only on the eye displacement vector of the trained saccade or 
      also on eye position information. Using the double-step target paradigm in eight 
      human subjects, we first induced in a single session two "opposite directions 
      adaptations" (ODA) of horizontal saccades of the same vector. Each ODA (backward 
      or forward) was linked to one vertical eye position (12.5 degrees up or 25 
      degrees down) and alternated from trial to trial. The results showed that 
      opposite changes of saccade amplitude can develop simultaneously, indicating that 
      saccadic adaptation depends on orbital eye position. This finding has important 
      functional implications because in everyday life our eyes saccade from constantly 
      changing orbital positions. A comparison of these data to two control conditions 
      in which training trials of a single type (backward or forward) were presented at 
      both 12.5 degrees and -25 degrees eye elevations further indicated that eye 
      position specificity is complete for backward, but not for forward, adaptation. 
      Finally, the control conditions also indicated that the adaptation of a single 
      saccade fully transferred to untrained saccades of the same vector, but initiated 
      from different vertical eye positions. In conclusion, our study indicates that 
      saccadic adaptation mechanisms use vectorial eye displacement signals, but can 
      also take eye position signals into account as a contextual cue when the training 
      involves conflicting saccade amplitude changes.
FAU - Alahyane, Nadia
AU  - Alahyane N
AD  - "Espace et Action" INSERM U534, IFR19 Institut Federatif des Neurosciences de 
      Lyon,16 avenue du doyen Lepine, 69500 Bron, France. pelisson@lyo.inserm.fr
FAU - Pelisson, Denis
AU  - Pelisson D
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Ann N Y Acad Sci
JT  - Annals of the New York Academy of Sciences
JID - 7506858
SB  - IM
MH  - Adaptation, Ocular/*physiology
MH  - Humans
MH  - Perception/physiology
MH  - Saccades/*physiology
MH  - *Transfer, Psychology
EDAT- 2003/12/10 05:00
MHDA- 2004/01/09 05:00
CRDT- 2003/12/10 05:00
PHST- 2003/12/10 05:00 [pubmed]
PHST- 2004/01/09 05:00 [medline]
PHST- 2003/12/10 05:00 [entrez]
AID - 10.1196/annals.1303.008 [doi]
PST - ppublish
SO  - Ann N Y Acad Sci. 2003 Oct;1004:69-77. doi: 10.1196/annals.1303.008.