PMID- 14671739 OWN - NLM STAT- MEDLINE DCOM- 20040707 LR - 20221207 IS - 0010-440X (Print) IS - 0010-440X (Linking) VI - 45 IP - 1 DP - 2004 Jan-Feb TI - Cincinnati criteria for mixed mania and suicidality in patients with acute mania. PG - 62-9 AB - The association between suicidality and diagnoses of mixed mania, as defined using both DSM-IV and Cincinnati criteria, was studied in 576 consecutive manic inpatients. Of the whole sample, 51 (8.9%) had suicidal ideation and 13 (2.3%) attempted suicide during the index episode. Suicidality was significantly more frequent in patients with a diagnosis of mixed mania, whether the diagnosis was made by DSM-IV or Cincinnati criteria. A multiple logistic regression analysis revealed that an additive combination of a diagnosis of mixed mania, the depression severity, and the Global Assessment of Functioning (GAF) score was significant in predicting suicidal ideation, when using the DSM-IV criteria. A diagnosis of mixed mania alone was significant in a similar analysis, when using the Cincinnati criteria. The adjusted odds ratio for a diagnosis of mixed mania to having suicidality was much higher when using the latter criteria (4.0 v 14.0). A subsequent logistic regression analysis indicated that the Cincinnati mixed mania alone, rather than an additive combination of the DSM-IV mixed mania and the depression severity, achieved the most appropriate prediction of suicidal ideation in the sample. These findings did not differ, even when suicidality was defined as having a suicide attempt during the index episode. Our finding that suicidality was more strongly associated with Cincinnati mixed mania than with DSM-IV mixed mania is probably due to that suicidal patients who do not meet DSM-IV criteria for mixed mania are classified into mixed mania, or/and that the depressive syndrome, related to suicidality, is more appropriately assessed among manic patients, when using the Cincinnati criteria. There was no evidence that marital status, employment, a lifetime history of alcohol or substance abuse, or a history of suicide attempts before the index episode was significantly associated with suicidality in the sample. Manic patients with suicidality may have a greater severity of residual depressive symptoms at discharge. FAU - Sato, Tetsuya AU - Sato T AD - Psychiatrische Klinik und Poliklinik, Ludwig-Maximilians-Universitat, Munchen, Germany. FAU - Bottlender, Ronald AU - Bottlender R FAU - Tanabe, Akira AU - Tanabe A FAU - Moller, Hans-Jurgen AU - Moller HJ LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - Compr Psychiatry JT - Comprehensive psychiatry JID - 0372612 SB - IM MH - Acute Disease MH - Adult MH - Bipolar Disorder/*diagnosis/epidemiology/psychology MH - Depressive Disorder/diagnosis/epidemiology/psychology MH - Diagnostic and Statistical Manual of Mental Disorders MH - Female MH - Germany MH - Humans MH - International Classification of Diseases MH - Logistic Models MH - Male MH - Middle Aged MH - Odds Ratio MH - Patient Admission MH - Personality Assessment/*statistics & numerical data MH - Psychometrics/statistics & numerical data MH - Reproducibility of Results MH - Risk Assessment/statistics & numerical data MH - Suicide/*psychology/statistics & numerical data MH - Suicide, Attempted/*psychology/statistics & numerical data MH - Suicide Prevention EDAT- 2003/12/13 05:00 MHDA- 2004/07/09 05:00 CRDT- 2003/12/13 05:00 PHST- 2003/12/13 05:00 [pubmed] PHST- 2004/07/09 05:00 [medline] PHST- 2003/12/13 05:00 [entrez] AID - S0010440X03001457 [pii] AID - 10.1016/S0010-440X(03)00145-7 [doi] PST - ppublish SO - Compr Psychiatry. 2004 Jan-Feb;45(1):62-9. doi: 10.1016/S0010-440X(03)00145-7.