PMID- 14674590
OWN - NLM
STAT- MEDLINE
DCOM- 20040106
LR  - 20190906
IS  - 0090-4341 (Print)
IS  - 0090-4341 (Linking)
VI  - 45
IP  - 3
DP  - 2003 Oct
TI  - Bioaccumulation of benzo(a)pyrene from sediment by fathead minnows: effects of 
      organic content, resuspension and metabolism.
PG  - 364-70
AB  - The accumulation of 14C-benzo(a)pyrene (BaP) sorbed to sediment was examined in 
      fathead minnows (Pimephales promelas) to compare uptake from sediment with a high 
      organic carbon (OC) content (7.7%), to that with a low OC content (2%). Ingestion 
      of sediments was quantified by co-labeling the sediment with 141Cerium, which was 
      not assimilated by the fish. Results of this study indicated that (1) 
      significantly greater quantities of BaP were dissolved in water over low-OC 
      sediment, compared to water over high-OC sediment, (2) fish disturbed the 
      sediment and increased the concentration of BaP in centrifuged (particle-free) 
      water, (3) fish ingested significantly more of the low-OC sediment than high-OC 
      sediment, perhaps in response to the lower food quality of the low-OC sediment, 
      and (4) uptake of BaP from sediment ingestion contributed <3% of the total flux 
      of BaP into the fish. Primarily as a result of the greater concentration of BaP 
      in water, fish from the low-OC exposures had significantly higher rates of BaP 
      accumulation. However, after 48 h the body burdens in these fish declined by 50%, 
      likely due to the induction of MFO enzymes in response to accumulation of BaP. A 
      smaller effect was apparent in the fish from the high-OC exposures, consistent 
      with the lower dose of BaP they experienced. These results illustrate the 
      complex, and sometime counterintuitive, interactions that affect the uptake and 
      bioaccumulation of sediment-associated contaminants.
FAU - McCarthy, J F
AU  - McCarthy JF
AD  - Department of Geological Sciences, University of Tennessee, 306 Geology Building, 
      Knoxville, Tennessee 37996-1410, USA. jmccart1@utk.edu
FAU - Burrus, L W
AU  - Burrus LW
FAU - Tolbert, V R
AU  - Tolbert VR
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Arch Environ Contam Toxicol
JT  - Archives of environmental contamination and toxicology
JID - 0357245
RN  - 0 (Carcinogens)
RN  - 0 (Organic Chemicals)
RN  - 0 (Water Pollutants, Chemical)
RN  - 3417WMA06D (Benzo(a)pyrene)
RN  - EC 1.- (Mixed Function Oxygenases)
SB  - IM
MH  - Animals
MH  - Benzo(a)pyrene/metabolism/*toxicity
MH  - Body Burden
MH  - Carcinogens/metabolism/*toxicity
MH  - Cyprinidae/*physiology
MH  - Geologic Sediments/chemistry
MH  - Mixed Function Oxygenases/pharmacology
MH  - Organic Chemicals
MH  - Water Pollutants, Chemical/metabolism/*toxicity
EDAT- 2003/12/17 05:00
MHDA- 2004/01/07 05:00
CRDT- 2003/12/17 05:00
PHST- 2003/12/17 05:00 [pubmed]
PHST- 2004/01/07 05:00 [medline]
PHST- 2003/12/17 05:00 [entrez]
AID - 10.1007/s00244-003-2148-0 [doi]
PST - ppublish
SO  - Arch Environ Contam Toxicol. 2003 Oct;45(3):364-70. doi: 
      10.1007/s00244-003-2148-0.