PMID- 14674841
OWN - NLM
STAT- MEDLINE
DCOM- 20040301
LR  - 20071115
IS  - 0735-7044 (Print)
IS  - 0735-7044 (Linking)
VI  - 117
IP  - 6
DP  - 2003 Dec
TI  - Cerebellar neuronal activity expresses the complex topography of conditioned 
      eyeblink responses.
PG  - 1211-9
AB  - Pavlovian eyeblink conditioning is a useful model system for studying how the 
      temporal relationship between a conditioned stimulus and an unconditioned 
      stimulus is represented in the brain. As an example, the response topography 
      formed under a complex conditioning paradigm, involving 2 randomly alternating 
      interstimulus intervals (ISIs), manifests a conditioned response (CR) with 2 
      distinctive peaks that correspond to the 2 ISIs. The authors present the first 
      full report of neuronal activities in the cerebellar interpositus nucleus of 
      rabbits performing bimodal responses. All CR-related activities exhibited firing 
      patterns that highly correlated with and preceded eyeblink responses. The 
      striking similarity between the time course of bimodal CRs and neuronal responses 
      indicates that neuronal activities in the cerebellum are causally related to the 
      production of behavioral CRs.
CI  - (c) 2003 APA
FAU - Choi, June-Seek
AU  - Choi JS
AD  - Neuroscience and Behavior Program, University of Massachusetts at Amherst, USA. 
      choi@cns.nyu.edu
FAU - Moore, John W
AU  - Moore JW
LA  - eng
GR  - MH-57893/MH/NIMH NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Behav Neurosci
JT  - Behavioral neuroscience
JID - 8302411
SB  - IM
MH  - Animals
MH  - *Brain Mapping
MH  - Cerebellum/*physiology
MH  - Conditioning, Eyelid/*physiology
MH  - Electrophysiology
MH  - Evoked Potentials/*physiology
MH  - Neurons/*physiology
MH  - Rabbits
MH  - Statistics as Topic
EDAT- 2003/12/17 05:00
MHDA- 2004/03/03 05:00
CRDT- 2003/12/17 05:00
PHST- 2003/12/17 05:00 [pubmed]
PHST- 2004/03/03 05:00 [medline]
PHST- 2003/12/17 05:00 [entrez]
AID - 2003-10460-009 [pii]
AID - 10.1037/0735-7044.117.6.1211 [doi]
PST - ppublish
SO  - Behav Neurosci. 2003 Dec;117(6):1211-9. doi: 10.1037/0735-7044.117.6.1211.