PMID- 14683715
OWN - NLM
STAT- MEDLINE
DCOM- 20040212
LR  - 20191108
IS  - 1053-8119 (Print)
IS  - 1053-8119 (Linking)
VI  - 20
IP  - 4
DP  - 2003 Dec
TI  - One brain, two selves.
PG  - 2119-25
AB  - Having a sense of self is an explicit and high-level functional specialization of 
      the human brain. The anatomical localization of self-awareness and the brain 
      mechanisms involved in consciousness were investigated by functional neuroimaging 
      different emotional mental states of core consciousness in patients with Multiple 
      Personality Disorder (i.e., Dissociative Identity Disorder (DID)). We demonstrate 
      specific changes in localized brain activity consistent with their ability to 
      generate at least two distinct mental states of self-awareness, each with its own 
      access to autobiographical trauma-related memory. Our findings reveal the 
      existence of different regional cerebral blood flow patterns for different senses 
      of self. We present evidence for the medial prefrontal cortex (MPFC) and the 
      posterior associative cortices to have an integral role in conscious experience.
FAU - Reinders, A A T S
AU  - Reinders AA
AD  - Department of Biological Psychiatry, Groningen University Hospital, The 
      Netherlands. a.a.t.s.reinders@med.rug.nl
FAU - Nijenhuis, E R S
AU  - Nijenhuis ER
FAU - Paans, A M J
AU  - Paans AM
FAU - Korf, J
AU  - Korf J
FAU - Willemsen, A T M
AU  - Willemsen AT
FAU - den Boer, J A
AU  - den Boer JA
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Neuroimage
JT  - NeuroImage
JID - 9215515
SB  - IM
MH  - Adult
MH  - Brain/diagnostic imaging/*physiopathology
MH  - Cerebrovascular Circulation/physiology
MH  - Dissociative Disorders/diagnostic imaging/physiopathology/psychology
MH  - Dissociative Identity Disorder/diagnostic imaging/*physiopathology/psychology
MH  - Female
MH  - Humans
MH  - Image Processing, Computer-Assisted
MH  - Middle Aged
MH  - Radionuclide Imaging
MH  - Wounds and Injuries/psychology
EDAT- 2003/12/20 05:00
MHDA- 2004/02/13 05:00
CRDT- 2003/12/20 05:00
PHST- 2003/12/20 05:00 [pubmed]
PHST- 2004/02/13 05:00 [medline]
PHST- 2003/12/20 05:00 [entrez]
AID - S1053811903005159 [pii]
AID - 10.1016/j.neuroimage.2003.08.021 [doi]
PST - ppublish
SO  - Neuroimage. 2003 Dec;20(4):2119-25. doi: 10.1016/j.neuroimage.2003.08.021.