PMID- 14685779
OWN - NLM
STAT- MEDLINE
DCOM- 20040331
LR  - 20240426
IS  - 0340-7004 (Print)
IS  - 1432-0851 (Electronic)
IS  - 0340-7004 (Linking)
VI  - 53
IP  - 3
DP  - 2004 Mar
TI  - Dendritic cell biology and cancer therapy.
PG  - 240-8
AB  - Dendritic cells (DCs) are nature's best antigen-presenting cells. They possess 
      attributes that allow them to effectively fulfill the requirements for 
      priming/activating T cells and mediating tumor-specific immune responses. In this 
      review, emphasis is placed on those aspects of DC biology that best illustrate 
      their usefulness in immunotherapy of cancer. Culture, maturation, and 
      polarization conditions for human DC are discussed, as are strategies for 
      antigen-loading of DCs and for their delivery to patients with cancer. A concise 
      recommendation for monitoring of DC-based vaccination trails is provided.
FAU - Whiteside, Theresa L
AU  - Whiteside TL
AD  - Research Pavilion at the Hillman Cancer Center, University of Pittsburgh Cancer 
      Institute, 5117 Centre Avenue, Suite 1.27, PA 15213-1863, Pittsburgh, USA. 
      whitesidetl@msx.upmc.edu
FAU - Odoux, Christine
AU  - Odoux C
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20031218
PL  - Germany
TA  - Cancer Immunol Immunother
JT  - Cancer immunology, immunotherapy : CII
JID - 8605732
RN  - 0 (Antigens, Neoplasm)
SB  - IM
MH  - Animals
MH  - Antigens, Neoplasm/immunology
MH  - Cell Movement
MH  - Cells, Cultured
MH  - Dendritic Cells/immunology/*physiology
MH  - Humans
MH  - Immunotherapy/*methods
MH  - Neoplasms/*therapy
PMC - PMC11034253
EDAT- 2003/12/20 05:00
MHDA- 2004/04/01 05:00
PMCR- 2003/12/18
CRDT- 2003/12/20 05:00
PHST- 2003/09/12 00:00 [received]
PHST- 2003/10/24 00:00 [accepted]
PHST- 2003/12/20 05:00 [pubmed]
PHST- 2004/04/01 05:00 [medline]
PHST- 2003/12/20 05:00 [entrez]
PHST- 2003/12/18 00:00 [pmc-release]
AID - 468 [pii]
AID - 10.1007/s00262-003-0468-6 [doi]
PST - ppublish
SO  - Cancer Immunol Immunother. 2004 Mar;53(3):240-8. doi: 10.1007/s00262-003-0468-6. 
      Epub 2003 Dec 18.