PMID- 14696844
OWN - NLM
STAT- MEDLINE
DCOM- 20040408
LR  - 20131121
IS  - 0803-5253 (Print)
IS  - 0803-5253 (Linking)
VI  - 92
IP  - 11
DP  - 2003 Nov
TI  - The importance of diet on exposure to and effects of persistent organic 
      pollutants on human health in the Arctic.
PG  - 1255-66
AB  - AIM: To describe the importance of diet on exposure to and possible health 
      effects of persistent organic pollutants (POPs) in the Arctic. METHODS: The study 
      is based on a literature review. RESULTS: Minor decreases in POPs and minor 
      increases in Hg levels in Arctic populations in Greenland, Eastern Russia, 
      Western Alaska and Eastern Canada are likely to occur by the year 2010 and major 
      decreases in both POPs and Hg levels in these same populations by 2030. Levels of 
      POPs and metals in populations in the Faeroe Islands and the Scandinavian 
      countries are already reasonably low and are only likely to decline marginally by 
      2030. Estimating the effects on the basis of current knowledge is difficult, but 
      the combination of improved methodology and selection of risk groups will be a 
      progressive step in the process. Any strategies based on traditional food 
      substitution should ensure that the value of the dietary components is sustained. 
      CONCLUSIONS: To improve our understanding of the health effects associated with 
      exposure to contaminants in the Arctic, we recommend that circumpolar 
      epidemiological studies should be implemented on a larger scale. MeHg- and 
      POPs-related effects are still the key issues. However, the role of newly 
      discovered contaminants, such as PBDEs (polybrominated diphenyl ethers) and PCNs 
      (polychlorinated naphthalenes), should be investigated. For exposure assessment, 
      mixtures and nutritional interactions should be considered in epidemiological 
      studies. Epidemiological studies on nutritional benefits of traditional foods 
      should be incorporated in risk-assessment profiles. We need a more nuanced view 
      on human dietary exposure to xenobiotics. Risk should not be evaluated alone, but 
      seen in relation to benefits from specific diets. It is essential that countries 
      ratify and implement multinational environmental agreements.
FAU - Odland, J O
AU  - Odland JO
AD  - Institute of Community Medicine, University of Tromso, Norway. 
      jon.oyvind.odland@ism.uit.no
FAU - Deutch, B
AU  - Deutch B
FAU - Hansen, J C
AU  - Hansen JC
FAU - Burkow, I C
AU  - Burkow IC
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - Norway
TA  - Acta Paediatr
JT  - Acta paediatrica (Oslo, Norway : 1992)
JID - 9205968
RN  - 0 (Dioxins)
RN  - 0 (Environmental Pollutants)
RN  - 0 (Metals, Heavy)
RN  - 0 (Organic Chemicals)
RN  - DFC2HB4I0K (Polychlorinated Biphenyls)
SB  - IM
CIN - Acta Paediatr. 2003 Nov;92(11):1238-40. PMID: 14696839
MH  - Arctic Regions
MH  - *Diet
MH  - Dioxins/blood
MH  - Environmental Exposure/*adverse effects
MH  - Environmental Pollutants/*blood
MH  - Food Chain
MH  - Food Contamination
MH  - *Health Status
MH  - Humans
MH  - Metals, Heavy/blood
MH  - Organic Chemicals/blood
MH  - Polychlorinated Biphenyls/blood
MH  - Risk Assessment
RF  - 41
EDAT- 2003/12/31 05:00
MHDA- 2004/04/09 05:00
CRDT- 2003/12/31 05:00
PHST- 2003/12/31 05:00 [pubmed]
PHST- 2004/04/09 05:00 [medline]
PHST- 2003/12/31 05:00 [entrez]
PST - ppublish
SO  - Acta Paediatr. 2003 Nov;92(11):1255-66.