PMID- 14697952
OWN - NLM
STAT- MEDLINE
DCOM- 20040818
LR  - 20190713
IS  - 0041-1345 (Print)
IS  - 0041-1345 (Linking)
VI  - 35
IP  - 8
DP  - 2003 Dec
TI  - Anesthetic management and complications in living donor hepatectomy.
PG  - 2970-3
AB  - A total of 112 living donor hepatectomies (LDHs) performed from October 1999 to 
      April 2003 at Ege University Hospital Organ Transplantation Center were reviewed 
      and perioperative anesthetic courses and complications were determined. There was 
      no perioperative mortality. Mean duration of operations was 333 +/- 77 minutes 
      (range, 160 to 540 minutes) for right lobectomies and 277 +/- 88 minutes (range, 
      150 to 500 minutes) for left lateral segment plus left lobe operations. The 
      remnant liver volume ratios of the patients was 0.58 +/- 0.16 (range, 0.30 to 
      0.91) after harvesting. Crystalloids, colloid infusions, and transfusions aimed 
      to keep hematocrit >25%, central venous pressure (CVP) <5 mm Hg and to maintain a 
      urine output >1 mL/kg(-1) while nitroglycerin was infused (0.5 to 2.0 
      microg/kg(-1)h(-1)) when needed to allow fluid infusions freely without 
      increasing the CVP values. No transfusion was needed for 91 patients (81%) and 21 
      right lobectomy patients needed transfusion of blood products. Initial mean 
      hematocrit of 38.9 +/- 4.9% (range, 27% to 50%) for all patients was found 31.5% 
      +/- 5% (21% to 44%) at the end of the operation. Albumin blood levels averaged 
      4.27 +/- 0.49 g/dL(-1) at the beginning and 3.28 +/- 0.45 g/dL(-1) after hepatic 
      resection. Perioperative complications were one air embolism, postoperative 
      systemic inflammatory response syndrome in one patient, transient but severe 
      hemoglobinuria due to a predonated autologous blood transfusion in another, 
      prolonged recovery for neuromuscular blocker overdose in one patient, and 
      postoperative atelectasis in three patients, two of whom had pneumonia later 
      while two other patients had pleural effusions. One required a drainage. Living 
      donor hepatectomies were performed with acceptable complications in anesthetic 
      management during this study. The operation provides us with an optimal liver 
      segment without resulting in mortality.
FAU - Ayanoglu, H O
AU  - Ayanoglu HO
AD  - Department of Anesthesiology and Reanimation, Ege University Medical School, 
      Izmir 35100, Turkey. ayanoglu@med.ege.edu.tr
FAU - Ulukaya, S
AU  - Ulukaya S
FAU - Yuzer, Y
AU  - Yuzer Y
FAU - Tokat, Y
AU  - Tokat Y
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Transplant Proc
JT  - Transplantation proceedings
JID - 0243532
SB  - IM
MH  - Anesthesia/*adverse effects/methods
MH  - Blood Component Transfusion
MH  - Hematocrit
MH  - Hemodynamics
MH  - Hemoglobinuria
MH  - Hepatectomy/adverse effects/*methods
MH  - Humans
MH  - Liver Function Tests
MH  - *Living Donors
MH  - Monitoring, Intraoperative
MH  - Postoperative Complications/epidemiology
MH  - Retrospective Studies
MH  - Tissue and Organ Harvesting/adverse effects/*methods
EDAT- 2003/12/31 05:00
MHDA- 2004/08/19 05:00
CRDT- 2003/12/31 05:00
PHST- 2003/12/31 05:00 [pubmed]
PHST- 2004/08/19 05:00 [medline]
PHST- 2003/12/31 05:00 [entrez]
AID - S0041134503012004 [pii]
AID - 10.1016/j.transproceed.2003.10.090 [doi]
PST - ppublish
SO  - Transplant Proc. 2003 Dec;35(8):2970-3. doi: 10.1016/j.transproceed.2003.10.090.