PMID- 14710823
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20041005
LR  - 20190717
IS  - 0003-2700 (Print)
IS  - 0003-2700 (Linking)
VI  - 75
IP  - 20
DP  - 2003 Oct 15
TI  - Microchip capillary electrophoresis with an integrated indium tin oxide 
      electrode-based electrochemiluminescence detector.
PG  - 5435-40
AB  - This paper describes an indium tin oxide (ITO) electrode-based Ru(bpy)3(2+) 
      electrochemiluminecence (ECL) detector for a microchip capillary electrophoresis 
      (CE). The microchip CE-ECL system described in this article consists of a 
      poly(dimethylsiloxane) (PDMS) layer containing separation and injection channels 
      and an electrode plate with an ITO electrode fabricated by a photolithographic 
      method. The PDMS layer was reversibly bound to the ITO electrode plate, which 
      greatly simplified the alignment of the separation channel with the working 
      electrode and enhanced the photon-capturing efficiency. In our study, the high 
      separation electric field had no significant influence on the ECL detector, and 
      decouplers for isolating the separation electric field were not needed in the 
      microchip CE-ECL system. The ITO electrodes employed in the experiments displayed 
      good durability and stability in the analytical procedures. Proline was selected 
      to perform the microchip device with a limit of detection of 1.2 microM (S/N = 3) 
      and a linear range from 5 to 600 microM.
FAU - Qiu, Haibo
AU  - Qiu H
AD  - State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of 
      Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, China.
FAU - Yan, Jilin
AU  - Yan J
FAU - Sun, Xiuhua
AU  - Sun X
FAU - Liu, Jifeng
AU  - Liu J
FAU - Cao, Weidong
AU  - Cao W
FAU - Yang, Xiurong
AU  - Yang X
FAU - Wang, Erkang
AU  - Wang E
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Anal Chem
JT  - Analytical chemistry
JID - 0370536
EDAT- 2004/01/09 05:00
MHDA- 2004/01/09 05:01
CRDT- 2004/01/09 05:00
PHST- 2004/01/09 05:00 [pubmed]
PHST- 2004/01/09 05:01 [medline]
PHST- 2004/01/09 05:00 [entrez]
AID - 10.1021/ac034500x [doi]
PST - ppublish
SO  - Anal Chem. 2003 Oct 15;75(20):5435-40. doi: 10.1021/ac034500x.