PMID- 147119
OWN - NLM
STAT- MEDLINE
DCOM- 19780517
LR  - 20190501
IS  - 0007-1447 (Print)
IS  - 0007-1447 (Linking)
VI  - 1
IP  - 6112
DP  - 1978 Mar 4
TI  - Human leucocyte antigens and mixed lymphocyte reaction in severe pre-eclampsia.
PG  - 542-4
AB  - Human leucocyte antigens (HLA) and mixed lymphocyte reactions (MLR) were studied 
      in 38 women with severe pre-eclampsia and their husbands. Thirty-nine women with 
      normal pregnancies and their husbands served as controls. Thirty-three of the 
      control women were matched for age and parity with members of the study group. 
      Infants were studied when possible. HLA compatibility was increased in the 
      pre-eclamptic group compared with matched controls and with theoretical estimates 
      for possible matings. The one-way MLR at delivery showed diminished response of 
      maternal to paternal and cord cells in pre-eclamptic women. This reduced maternal 
      reactivity in women with pre-eclampsia may have a role in the illness, and 
      paternal/maternal histocompatibility may be a feature of the severe form.
FAU - Jenkins, D M
AU  - Jenkins DM
FAU - Need, J A
AU  - Need JA
FAU - Scott, J S
AU  - Scott JS
FAU - Morris, H
AU  - Morris H
FAU - Pepper, M
AU  - Pepper M
LA  - eng
PT  - Journal Article
PL  - England
TA  - Br Med J
JT  - British medical journal
JID - 0372673
RN  - 0 (HLA Antigens)
SB  - IM
MH  - Female
MH  - HLA Antigens/*analysis
MH  - Histocompatibility
MH  - Humans
MH  - Lymphocyte Culture Test, Mixed
MH  - Lymphocytes/physiology
MH  - Male
MH  - Pre-Eclampsia/*immunology
MH  - Pregnancy
PMC - PMC1603239
EDAT- 1978/03/04 00:00
MHDA- 1978/03/04 00:01
PMCR- 1978/03/04
CRDT- 1978/03/04 00:00
PHST- 1978/03/04 00:00 [pubmed]
PHST- 1978/03/04 00:01 [medline]
PHST- 1978/03/04 00:00 [entrez]
PHST- 1978/03/04 00:00 [pmc-release]
AID - 10.1136/bmj.1.6112.542 [doi]
PST - ppublish
SO  - Br Med J. 1978 Mar 4;1(6112):542-4. doi: 10.1136/bmj.1.6112.542.