PMID- 14714767
OWN - NLM
STAT- MEDLINE
DCOM- 20050404
LR  - 20170214
IS  - 0267-6591 (Print)
IS  - 0267-6591 (Linking)
VI  - 18
IP  - 6
DP  - 2003 Nov
TI  - Carotid Doppler microembolic signals in patients one year after heart valve 
      surgery.
PG  - 333-7
AB  - Doppler ultrasound has been used to detect microemboli during and after 
      cardiopulmonary bypass (CPB). The aim of the present study was to examine the 
      frequency of microembolic signals (MES) in patients one year after heart valve 
      replacement, to look for possible risk factors associated with MES and for any 
      correlation with cerebral events. One hundred patients, 69 male and 31 female, 
      mean age 66.3 +/- 12.4 years, were examined one year after heart valve 
      replacement. Thirty patients, 61% male and 39% female, mean age 62.5 +/- 8.7 
      years, who had undergone cardiovascular operations without heart valve pathology 
      served as controls. A newly developed microemboli detector, EMEX-25 (Hatteland 
      Instrumentering, Norway) was used to detect MES from both carotid arteries. MES 
      were detected in 61% of the valve patients. A correlation was found between the 
      number of MES, previous cardiovascular operations, emergency surgery and 
      EuroSCORE (p <0.05). There was no correlation between the number of MES and the 
      level of anticoagulation expressed as international normalization ratio (INR), 
      atrial fibrillation, serum-cholesterol, New York heart association (NYHA) class, 
      gender, age, valve type or valve position. The average number of MES was not 
      increased in seven patients who had experienced major (three) or minor 
      (transient, four) cerebral events during follow-up. In the 30 nonvalve controls, 
      MES were detected in 46% of the patients. MES were detected in valve patients as 
      well as in nonvalve patients one year after surgery. In valve patients, a 
      significant correlation was found between MES and previous surgery, emergency 
      surgery and EuroSCORE. There was no correlation between the number of MES and INR 
      level or postoperative cerebral events.
FAU - Dalinin, Vadim
AU  - Dalinin V
AD  - Department of Thoracic and Cardiovascular Surgery, Rikshospitalet, University of 
      Oslo, Norway.
FAU - Lingaas, Per Snorre
AU  - Lingaas PS
FAU - Hatteland, Kjell
AU  - Hatteland K
FAU - Svennevig, Jan L
AU  - Svennevig JL
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - England
TA  - Perfusion
JT  - Perfusion
JID - 8700166
SB  - IM
MH  - Aged
MH  - Carotid Artery Thrombosis/diagnostic imaging/epidemiology/*etiology
MH  - Cerebral Arteries/diagnostic imaging/physiopathology
MH  - Female
MH  - Heart Valve Diseases/diagnostic imaging/surgery
MH  - Heart Valve Prosthesis Implantation/*adverse effects/statistics & numerical data
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Risk Factors
MH  - Ultrasonography, Doppler/instrumentation
EDAT- 2004/01/13 05:00
MHDA- 2005/04/05 09:00
CRDT- 2004/01/13 05:00
PHST- 2004/01/13 05:00 [pubmed]
PHST- 2005/04/05 09:00 [medline]
PHST- 2004/01/13 05:00 [entrez]
AID - 10.1191/0267659103pf692oa [doi]
PST - ppublish
SO  - Perfusion. 2003 Nov;18(6):333-7. doi: 10.1191/0267659103pf692oa.