PMID- 14734926
OWN - NLM
STAT- MEDLINE
DCOM- 20041103
LR  - 20091111
IS  - 0020-9996 (Print)
IS  - 0020-9996 (Linking)
VI  - 39
IP  - 2
DP  - 2004 Feb
TI  - Renal embolization: feasibility of magnetic resonance-guidance using active 
      catheter tracking and intraarterial magnetic resonance angiography.
PG  - 111-9
AB  - RATIONALE AND OBJECTIVES: Magnetic resonance (MR)-guidance of endovascular 
      interventions offers various advantages, including the absence of ionizing 
      radiation, excellent soft tissue contrast, and multiplanar and functional imaging 
      capabilities. The objective of this study was to assess the feasibility of 
      MR-guided renal embolization using active catheter tracking with automatic slice 
      positioning and intraarterial contrast-enhanced MR angiography (MRA). MATERIALS 
      AND METHODS: MR-guided embolization of 16 kidneys was attempted in 15 pigs using 
      real-time tracking of active 5-Fr. catheters. Embolization was monitored by 
      selective intraarterial projection MRA. Intraarterial three-dimensional (3D) MRA 
      was used for the assessment of embolization results. Additional pathologic 
      correlation was available in 2 animals. The image quality of intraarterial 3D 
      contrast-enhanced-MRA was rated by an independent radiologist who was not 
      involved in the animal experiments. RESULTS: Active catheter tracking with 
      automatic slice positioning allowed reliable catheter guidance and 
      catheterization of the renal artery in all animals. Embolization was successful 
      in all kidneys (11 left, 5 right), as verified by intraarterial 3D 
      contrast-enhanced MRA (ce-MRA) and/or pathology. The image quality of 
      intraarterial 3D ce-MRA was rated excellent in 10 animals, moderate in 4 animals, 
      and poor in 1 animal. CONCLUSION: Renal embolization using active catheter 
      tracking and intraarterial ce-MRA is feasible. Selective intraarterial ce-MRA 
      allows the assessment of blood supply and organ perfusion before, during, and 
      after therapeutic interventions, thereby complementing MR-guided endovascular 
      interventions.
FAU - Fink, Christian
AU  - Fink C
AD  - Department of Radiology (E010), Deutsches Krebsforschungszentrum (DKFZ), 
      Heidelberg, Germany. c.fink@dkfz.de
FAU - Bock, Michael
AU  - Bock M
FAU - Umathum, Reiner
AU  - Umathum R
FAU - Volz, Steffen
AU  - Volz S
FAU - Zuehlsdorff, Sven
AU  - Zuehlsdorff S
FAU - Grobholz, Rainer
AU  - Grobholz R
FAU - Kauczor, Hans-Ulrich
AU  - Kauczor HU
FAU - Hallscheidt, Peter
AU  - Hallscheidt P
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Invest Radiol
JT  - Investigative radiology
JID - 0045377
SB  - IM
MH  - Animals
MH  - Carcinoma, Renal Cell/therapy
MH  - Catheterization, Peripheral
MH  - Disease Models, Animal
MH  - Embolization, Therapeutic/*methods
MH  - Kidney Neoplasms/therapy
MH  - *Magnetic Resonance Angiography
MH  - Magnetic Resonance Imaging
MH  - *Renal Artery
MH  - Swine
EDAT- 2004/01/22 05:00
MHDA- 2004/11/04 09:00
CRDT- 2004/01/22 05:00
PHST- 2004/01/22 05:00 [pubmed]
PHST- 2004/11/04 09:00 [medline]
PHST- 2004/01/22 05:00 [entrez]
AID - 00004424-200402000-00007 [pii]
AID - 10.1097/01.rli.0000110744.70512.df [doi]
PST - ppublish
SO  - Invest Radiol. 2004 Feb;39(2):111-9. doi: 10.1097/01.rli.0000110744.70512.df.