PMID- 14737964
OWN - NLM
STAT- MEDLINE
DCOM- 20040330
LR  - 20051117
VI  - 48
DP  - 2003
TI  - The pattern--reversal visual evoked potentials in children with migraine with 
      aura and without aura.
PG  - 154-7
AB  - PURPOSE: Studies of the visual evoked potentials (VEP) in migraine have yielded 
      contradictory results. Several investigators suggested that VEP may be helpful 
      test in diagnosis of a child with headache. The aim of our study was to compare 
      interictal pattern-reversal visual evoked potentials (PR-VEP) in children and 
      adolescents with migraine and tension-type headaches and to evaluate VEP 
      parameters in migraine with and without aura. MATERIAL AND METHODS: The study was 
      carried out in 93 children and adolescents aged 7-18 years with attack headaches. 
      RESULTS: 51 children had diagnosed migraine. In this group 30 children (59%) had 
      migraine without aura (MO), 12 children (23.5%) migraine with aura (MA) and 9 
      (17.5%) patients other variants of migraine (MV): hemiplegic, ophthalmoplegic, 
      basilar. In control group 42 children were classified as tension-type headaches. 
      All children had PR-VEP performed in headache-free period, without prophylactic 
      treatment. The P100 mean latency was significantly longer in migraine than in 
      tension-type headache. Amplitudes N1-P100 and P100-N2 were significantly larger 
      in migraneurs compared with tension-type headache. The mean amplitudes of N1-P100 
      and P100-N2 were significantly lower in MA compared with group MO. There were no 
      statistically significant differences of other PR-VEP parameters between MA, MO, 
      MV. If we compare individual results of each patient with migraine with mean 
      value +/- 2 standard deviations (SD) of tension-type headaches group, only 25% 
      have VEP abnormalities of latency or amplitude above 2SD value in tension-type 
      headache group. CONCLUSIONS: The diagnosis of migraine in children actually 
      remains predominantly based on medical history, due to low sensitivity and 
      specificity of electrodiagnostic tests in headaches. However PR-VEP may support 
      the diagnosis of migraine in some cases. VEP could be also helpful method in 
      studying the pathogenesis of different forms of migraine. VEP abnormalities in 
      migraine can be related to a cortical spreading depression and a central 
      neurotransmitter alterations.
FAU - Bockowski, L
AU  - Bockowski L
AD  - Department of Pediatric Neurology, Medical University of Bialystok, SP DSK, ul. 
      Waszyngtona 17, 15-274 Bialystok, Poland. bockow@kki.pl
FAU - Sobaniec, W
AU  - Sobaniec W
FAU - Smigielska-Kuzia, J
AU  - Smigielska-Kuzia J
FAU - Kulak, W
AU  - Kulak W
FAU - Solowiej, E
AU  - Solowiej E
LA  - eng
PT  - Journal Article
PL  - Poland
TA  - Rocz Akad Med Bialymst
JT  - Roczniki Akademii Medycznej w Bialymstoku (1995)
JID - 9515551
SB  - IM
MH  - Adolescent
MH  - Child
MH  - Evoked Potentials, Visual/*physiology
MH  - Female
MH  - Humans
MH  - Male
MH  - Migraine Disorders/*physiopathology
MH  - Tension-Type Headache/physiopathology
EDAT- 2004/01/24 05:00
MHDA- 2004/03/31 05:00
CRDT- 2004/01/24 05:00
PHST- 2004/01/24 05:00 [pubmed]
PHST- 2004/03/31 05:00 [medline]
PHST- 2004/01/24 05:00 [entrez]
PST - ppublish
SO  - Rocz Akad Med Bialymst. 2003;48:154-7.