PMID- 14749924 OWN - NLM STAT- MEDLINE DCOM- 20040629 LR - 20181113 IS - 0340-6199 (Print) IS - 0340-6199 (Linking) VI - 163 IP - 3 DP - 2004 Mar TI - Wheeze and urban variation in South Asia. PG - 145-7 AB - Typically, urban South Asia is characterised by narrow streets, heavy traffic, visible haze, unplanned city architecture and the use of kerosene or wood-burning stoves at home. However, some urban areas in South Asia are clean and modern, with concrete housing, vehicle emission regulations and use of smoke-free household fuel. The purpose of this study was to compare wheeze prevalence in 13-14-year-olds between two South Asian cities (Galle, Chandigarh), representing each of the above two archetypes. The validated one-page International Study on Asthma and Allergies in Childhood (ISAAC) questionnaire for 13-14-year-olds was used for the study. Of 1814 distributed questionnaires, 1737 (95.8%) were completed correctly and returned (Galle: n=1162; Chandigarh: n=575). Crude prevalence rates, and prevalence odds ratios (with 95% two-sided confidence intervals (CI) for comparison of prevalence rates), were calculated. The prevalence rate for wheezing in Galle (28.7%) was higher than in Chandigarh (12.5%). The prevalence odds ratios (Galle versus Chandigarh) for lifetime wheezing (2.3; 1.8-2.9), wheezing in the previous year (2.1; 1.6-2.7), exercise-related wheeze (4.8; 3.5-6.7) and physician-diagnosed wheeze (1.7; 1.2-2.3) demonstrated significant differences in wheeze prevalence between the two cities ( P<0.05). The numbers of 13-14-year-olds experiencing less than 12 wheezing episodes per year or sleep disturbance due to wheeze of less than 1 night per week were also significantly higher for Galle than Chandigarh. There is a higher prevalence of wheeze in 13-14-year-old children living in an old-fashioned, congested city than in a clean and modern city in South Asia. FAU - Mistry, Rikki AU - Mistry R AD - Tayside Institute of Child Health, Ninewells Hospital and Medical School, DD1 9SY, Dundee, Scotland, UK. FAU - Wickramasingha, Nandanee AU - Wickramasingha N FAU - Ogston, Simon AU - Ogston S FAU - Singh, Meenu AU - Singh M FAU - Devasiri, Vasantha AU - Devasiri V FAU - Mukhopadhyay, Somnath AU - Mukhopadhyay S LA - eng PT - Journal Article PT - Multicenter Study DEP - 20040129 PL - Germany TA - Eur J Pediatr JT - European journal of pediatrics JID - 7603873 SB - IM MH - Adolescent MH - Air Pollution/*adverse effects MH - Female MH - Humans MH - India/epidemiology MH - Male MH - Odds Ratio MH - Prevalence MH - Respiratory Hypersensitivity/*epidemiology/etiology MH - *Respiratory Sounds MH - Sri Lanka/epidemiology MH - Urban Population EDAT- 2004/01/30 05:00 MHDA- 2004/06/30 05:00 CRDT- 2004/01/30 05:00 PHST- 2003/08/12 00:00 [received] PHST- 2003/12/04 00:00 [accepted] PHST- 2004/01/30 05:00 [pubmed] PHST- 2004/06/30 05:00 [medline] PHST- 2004/01/30 05:00 [entrez] AID - 10.1007/s00431-003-1393-6 [doi] PST - ppublish SO - Eur J Pediatr. 2004 Mar;163(3):145-7. doi: 10.1007/s00431-003-1393-6. Epub 2004 Jan 29.