PMID- 14757917
OWN - NLM
STAT- MEDLINE
DCOM- 20040803
LR  - 20071114
IS  - 0957-4271 (Print)
IS  - 0957-4271 (Linking)
VI  - 13
IP  - 2-3
DP  - 2003
TI  - Otolith-ocular responses in patients with surgically confirmed unilateral 
      peripheral vestibular loss.
PG  - 143-51
AB  - The chronic effects of unilateral peripheral vestibular loss (UPVL) are 
      influenced by vestibular compensation. This study documents the balance-related 
      symptoms and quantitative vestibular laboratory testing of 20 patients with 
      surgically confirmed UPVL. Included are measures of the semicircular canal-ocular 
      reflex, the otolith-ocular reflex, and both static and dynamic semicircular 
      canal-otolith-interaction. This study differs from previous studies of patients 
      with UPVL in that a large number of patients with surgically confirmed lesions 
      were tested with three types of off-vertical axis rotation, several of the 
      patients had anatomically preserved superior vestibular nerves, and 
      self-perceived level of disability related to dizziness and imbalance were 
      available. Results confirmed previously reported changes in the vestibulo-ocular 
      reflex of patients with UPVL. Also, there was no apparent effect of anatomically 
      preserving the superior vestibular nerve during surgical resection of vestibular 
      schwannomas based on either subjective or objective measures of vestibular 
      dysfunction. Further, there were no apparent correlations between subjective 
      measures of dizziness and imbalance and objective measures of vestibulo-ocular 
      function. These results have clinical implications for the management of patients 
      with unilateral vestibular loss and provide insights into the process of 
      vestibular compensation especially with respect to the otolith-ocular reflex.
FAU - Furman, Joseph M
AU  - Furman JM
AD  - Department of Otolaryngology, University of Pittsburgh, PA, USA. furman@pitt.edu
FAU - Hsu, Li-Chi
AU  - Hsu LC
FAU - Whitney, Susan L
AU  - Whitney SL
FAU - Redfern, Mark S
AU  - Redfern MS
LA  - eng
GR  - DC03417/DC/NIDCD NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - Netherlands
TA  - J Vestib Res
JT  - Journal of vestibular research : equilibrium & orientation
JID - 9104163
SB  - IM
EIN - J Vestib Res. 2004;14(1):65
MH  - Adult
MH  - Aged
MH  - Disabled Persons
MH  - Dizziness/etiology/physiopathology
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Oculomotor Muscles/physiopathology
MH  - Otolithic Membrane/physiopathology
MH  - *Reflex, Vestibulo-Ocular
MH  - Semicircular Canals/physiopathology
MH  - Vestibular Diseases/complications/*physiopathology
MH  - Vestibular Function Tests
EDAT- 2004/02/06 05:00
MHDA- 2004/08/04 05:00
CRDT- 2004/02/06 05:00
PHST- 2004/02/06 05:00 [pubmed]
PHST- 2004/08/04 05:00 [medline]
PHST- 2004/02/06 05:00 [entrez]
PST - ppublish
SO  - J Vestib Res. 2003;13(2-3):143-51.