PMID- 1477613
OWN - NLM
STAT- MEDLINE
DCOM- 19930211
LR  - 20101118
IS  - 0941-2921 (Print)
IS  - 0941-2921 (Linking)
VI  - 1
IP  - 1
DP  - 1992
TI  - Diffuse field loss and diffuse retinal nerve-fiber loss in glaucoma.
PG  - 22-5
AB  - A total of 61 eyes of 61 patients were examined by light-sense, flicker and 
      resolution perimetry. All fields were classified as being normal or showing 
      diffuse loss, localized defects or diffuse plus localized loss. For the 
      assessment of diffuse field loss, cumulative defect curves were derived. Retinal 
      nerve-fiber layer (RNFL) loss was assessed by a semiquantitative scoring 
      technique. In light-sense and flicker perimetry, the total diffuse and total 
      overall RNFL scores for eyes with diffuse field loss were approximately twice 
      those obtained for eyes without diffuse field loss. These differences were highly 
      statistically significant (P = 0.0055 and 0.0087 for light-sense perimetry, P = 
      0.0033 and 0.0042 for flicker perimetry). In resolution perimetry, eyes with 
      diffuse field loss also showed higher RNFL scores; the differences, however, were 
      not statistically significant. The results show that diffuse field loss in 
      light-sense and flicker perimetry is accompanied by diffuse nerve-fiber loss.
FAU - Lachenmayr, B J
AU  - Lachenmayr BJ
AD  - Department of Ophthalmology, University of British Columbia, Vancouver, Canada.
FAU - Drance, S M
AU  - Drance SM
FAU - Airaksinen, P J
AU  - Airaksinen PJ
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Germany
TA  - Ger J Ophthalmol
JT  - German journal of ophthalmology
JID - 9206441
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Flicker Fusion
MH  - Glaucoma/pathology/*physiopathology
MH  - Humans
MH  - Light
MH  - Middle Aged
MH  - Nerve Fibers/pathology
MH  - Retinal Diseases/pathology/*physiopathology
MH  - Vision Disorders/pathology/*physiopathology
MH  - Visual Field Tests
MH  - *Visual Fields
EDAT- 1992/01/01 00:00
MHDA- 1992/01/01 00:01
CRDT- 1992/01/01 00:00
PHST- 1992/01/01 00:00 [pubmed]
PHST- 1992/01/01 00:01 [medline]
PHST- 1992/01/01 00:00 [entrez]
PST - ppublish
SO  - Ger J Ophthalmol. 1992;1(1):22-5.