PMID- 1486571 OWN - NLM STAT- MEDLINE DCOM- 19930225 LR - 20190815 IS - 0165-4608 (Print) IS - 0165-4608 (Linking) VI - 64 IP - 2 DP - 1992 Dec TI - Confirmation of centromeric fusion in 7p/1q translocation associated with myelodysplastic syndrome. PG - 186-8 AB - Fluorescence in situ hybridization (FISH) using chromosome 1- and chromosome 7-specific centromeric alpha-satellite probes was performed on the bone marrow (BM) cells of a patient with myelodysplastic syndrome (MDS) who had been treated for lymphoma and whose BM karyotype was initially considered to be 46,XY,-7,+der(1)t(1;7)(p11;p11). FISH results suggested the presence of both chromosome 1 and chromosome 7 centromeres in the rearranged chromosome. Thus, the correct karyotype should be written as 46,XY,-7,+der(1;7)(q10;p10). FAU - Hoo, J J AU - Hoo JJ AD - Office of Consolidated Laboratory Services, Rush-Presbyterian-St. Luke's Medical Center, Chicago, IL 60612. FAU - Szego, K AU - Szego K FAU - Jones, B AU - Jones B LA - eng PT - Case Reports PT - Journal Article PL - United States TA - Cancer Genet Cytogenet JT - Cancer genetics and cytogenetics JID - 7909240 RN - 0 (DNA Probes) RN - 0 (DNA, Satellite) SB - IM MH - Adult MH - Bone Marrow/pathology MH - *Centromere MH - *Chromosomes, Human, Pair 1 MH - *Chromosomes, Human, Pair 7 MH - DNA Probes MH - DNA, Satellite MH - Humans MH - In Situ Hybridization, Fluorescence MH - Karyotyping MH - Lymphoma/complications/therapy MH - Male MH - Myelodysplastic Syndromes/complications/*genetics MH - *Translocation, Genetic EDAT- 1992/12/01 00:00 MHDA- 1992/12/01 00:01 CRDT- 1992/12/01 00:00 PHST- 1992/12/01 00:00 [pubmed] PHST- 1992/12/01 00:01 [medline] PHST- 1992/12/01 00:00 [entrez] AID - 0165-4608(92)90354-B [pii] AID - 10.1016/0165-4608(92)90354-b [doi] PST - ppublish SO - Cancer Genet Cytogenet. 1992 Dec;64(2):186-8. doi: 10.1016/0165-4608(92)90354-b.